anti-Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) Anticorps

The protein encoded by UBR4 is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. De plus, nous expédions UBR4 Kits (15) et et beaucoup plus de produits pour cette protéine.

afficher tous les anticorps Gène GeneID UniProt
UBR4 23352 Q5T4S7
UBR4 69116 A2AN08
UBR4 313658 Q2TL32
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Top anti-UBR4 Anticorps sur anticorps-enligne.fr

Showing 10 out of 34 products:

Catalogue No. Reactivité Hôte Conjugué Application Images Quantité Fournisseur Livraison Prix Détails
Humain Lapin Inconjugué ICC, IF, IHC, IHC (p), IP, WB Western Blot: UBR4 Antibody [NBP1-28730] - Detection of Human p600 on HeLa whole cell lysate using NBP28730. p600 was also immunoprecipitated by rabbit anti-p600 antibodies NBP1-28683 and NBP1-28724. Immunohistochemistry-Paraffin: UBR4 Antibody [NBP1-28730] - section of human prostate carcinoma. 100 μL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Roussette (Chauve-souris) Chèvre Inconjugué IHC (p), ELISA Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Connectez-vous pour afficher 11 to 14 Days
705,40 €
Détails
Humain Chèvre Inconjugué ELISA, IHC   0.1 mg Connectez-vous pour afficher 3 to 5 Days
388,75 €
Détails
Humain Lapin Inconjugué IHC, IHC (p)   0.1 mL Connectez-vous pour afficher 6 to 9 Days
418,75 €
Détails
Humain Souris Inconjugué IF Immunofluorescence of to RBAF600 on HeLa cell . Detection limit for recombinant GST tagged RBAF600 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Connectez-vous pour afficher 12 to 16 Days
454,76 €
Détails
Humain Lapin Inconjugué IHC, IHC (p), WB Immunohistochemistry-Paraffin: UBR4 Antibody [NBP1-28724] - FFPE section of human prostate carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. 0.1 mL Connectez-vous pour afficher 3 to 5 Days
463,75 €
Détails
Humain Chèvre Inconjugué ELISA   0.1 mg Connectez-vous pour afficher 6 to 8 Days
505,48 €
Détails
Humain Souris Inconjugué IF, ELISA, WB Immunofluorescence of monoclonal antibody to RBAF600 on HeLa cell. [antibody concentration 10 ug/ml] Detection limit for recombinant GST tagged RBAF600 is approximately 0.1ng/ml as a capture antibody. 100 μg Connectez-vous pour afficher 7 to 8 Days
369,60 €
Détails
Humain Souris APC ICC, ELISA, WB   100 μL Connectez-vous pour afficher 11 to 14 Days
1.098,26 €
Détails
Humain Souris FITC ICC, ELISA, WB   100 μL Connectez-vous pour afficher 11 to 14 Days
1.098,26 €
Détails

UBR4 Anticorps par réactivité, application, clonalité et conjugué

Attributs Application Hôte Clonalité Conjugué
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anti-UBR4 Anticorps mieux référencés

  1. Human Polyclonal UBR4 Primary Antibody pour ICC, IF - ABIN440546 : Corteggio, Di Geronimo, Roperto, Roperto, Borzacchiello: Bovine papillomavirus E7 oncoprotein binds to p600 in naturally occurring equine sarcoids. dans The Journal of general virology 2011 (PubMed)

  2. Human Polyclonal UBR4 Primary Antibody pour IHC, IHC (p) - ABIN4364020 : Ling, Beaulé, Chiang, Tian, Figeys, Cheng: Time-of-day- and light-dependent expression of ubiquitin protein ligase E3 component N-recognin 4 (UBR4) in the suprachiasmatic nucleus circadian clock. dans PLoS ONE 2014 (PubMed)

  3. Human Polyclonal UBR4 Primary Antibody pour ELISA, IHC - ABIN4364019 : Lennerz, Fatho, Gentilini, Frye, Lifke, Ferel, Wölfel, Huber, Wölfel: The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. dans Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

Plus d’anticorps contre UBR4 partenaires d’interaction

Human Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) interaction partners

  1. Ubiquitin ligase Ubr4 is a key component of the podocin interactome purified from podocytes. Ubiquitylation of one podocin site, K301, do not only target podocin for proteasomal degradation, but may also affect stability and disassembly of the multimeric complex.

  2. Results showed KCMF1 (Montrer KCMF1 Anticorps) C-terminus binds directly to RAD6, whereas N-terminal domains interact with UBR4 and point mutations found in X-linked intellectual disability (XLID) patients specifically lose the interaction with KCMF1 (Montrer KCMF1 Anticorps) and UBR4.

  3. This review summarizes the central nervous system functions of p600 (Montrer IL13 Anticorps) and proposes new perspectives on its biological complexity in neuronal physiology and neurological diseases.

  4. Although UBR4 is not an ion channel gene, the potential for disrupted Ca(2 (Montrer CA2 Anticorps)+) control within neuronal cells highlights its potential for a role in this form of episodic ataxia (Montrer USP14 Anticorps).

  5. Dengue virus co-opts UBR4 to degrade STAT2 (Montrer STAT2 Anticorps) and antagonize type I interferon (Montrer IFNA Anticorps) signaling.

  6. Human papillomavirus E7 oncoprotein associates with p600 (Montrer IL13 Anticorps); interaction strongly contributes to cellular transformation independent of ability of E7 to bind pRB (Montrer RB1 Anticorps).

  7. Results identify and characterize p600, a unique 600-kDa retinoblastoma protein- and calmodulin-binding protein.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 4 (UBR4) interaction partners

  1. Ubiquitin ligase Ubr4 is a key component of the podocin interactome purified from cultured podocytes and native glomeruli. Ubiquitylomic analysis of mouse glomeruli revealed that podocin is ubiquitylated at two lysine residues. Ubiquitylation of one podocin site, K301, do not only target podocin for proteasomal degradation, but may also affect stability and disassembly of the multimeric complex.

  2. This study is the first to identify a novel E3 ubiquitin ligase (Montrer MUL1 Anticorps) component, UBR4, in the murine SCN (Montrer SRI Anticorps) and to implicate the N-end rule degradation pathway as a potential player in regulating core clock mechanisms and photic entrainment.

  3. UBR4-deficient mice die during embryogenesis and exhibit pleiotropic abnormalities, including impaired vascular development in the yolk sac (Montrer ADCY10 Anticorps).

  4. Found murine p600 (formally called RBAF600) copurified with the E7 oncoprotein in C127 cells. This interaction was found to correlate with the ability of E7 to increase transformation.

  5. This study identified protein 600 (p600) as a novel microtubule-associated protein (Montrer SPAG5 Anticorps) (MAP) developmentally regulated in neurons. p600 exhibits the unique feature to interact with the endoplasmic reticulum (ER).

  6. Member of UBR box protein family, termed Ubr4. Binds to destabilizing N-terminal residues of N-end rule substrates. Participates in degradation of N-end rule substrates.

UBR4 profil antigène

Profil protéine

The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.

Gene names and symbols associated with UBR4

  • ubiquitin protein ligase E3 component n-recognin 4 (UBR4) anticorps
  • ubiquitin protein ligase E3 component n-recognin 4 (Ubr4) anticorps
  • 1810009A16Rik anticorps
  • A930005E13Rik anticorps
  • D930005K06Rik anticorps
  • Gm1032 anticorps
  • Gm1666 anticorps
  • mKIAA0462 anticorps
  • N28143 anticorps
  • p600 anticorps
  • Rbaf600 anticorps
  • Zubr1 anticorps

Protein level used designations for UBR4

retinoblastoma-associated factor 600 , zinc finger, UBR1 type 1 , E3 ubiquitin-protein ligase UBR4 , N-recognin-4 , retinoblastoma-associated factor 600-like protein , retinoblastoma-associated factor of 600 kDa , zinc finger UBR1-type protein 1 , ZUBR1

GENE ID SPECIES
456576 Pan troglodytes
23352 Homo sapiens
478211 Canis lupus familiaris
69116 Mus musculus
313658 Rattus norvegicus
100511934 Sus scrofa
419469 Gallus gallus
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