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VEGFD anticorps (Middle Region)

Cet anticorps Lapin Polyclonal détecte spécifiquement VEGFD dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 2+ publications.
N° du produit ABIN967243
412,50 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 8 à 12 jours ouvrables

Aperçu rapide pour VEGFD anticorps (Middle Region) (ABIN967243)

Antigène

Voir toutes VEGFD (Figf) Anticorps
VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

Reactivité

  • 74
  • 34
  • 27
  • 2
  • 2
Humain

Hôte

  • 64
  • 17
  • 1
Lapin

Clonalité

  • 54
  • 28
Polyclonal

Conjugué

  • 45
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp VEGFD est non-conjugé

Application

  • 67
  • 43
  • 25
  • 17
  • 14
  • 12
  • 12
  • 10
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Épitope

    • 13
    • 11
    • 10
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

     Réactivité croisée

    Souris, Rat (Rattus)

    Réactivité croisée (Details)

    No cross reactivity with other proteins.

    Attributs du produit

    Rabbit IgG polyclonal antibody for Vascular endothelial growth factor D (FIGF) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

    Immunogène

    A synthetic peptide corresponding to a sequence in the middle region of human VEGFD , identical to the related rat and mouse sequences.< br/>Immunogen was affinity purified.

    Isotype

    IgG
  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide, Thimerosal (Merthiolate)

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Stacker, Caesar, Baldwin, Thornton, Williams, Prevo, Jackson, Nishikawa, Kubo, Achen: "VEGF-D promotes the metastatic spread of tumor cells via the lymphatics." dans: Nature medicine, Vol. 7, Issue 2, pp. 186-91, (2001) (PubMed).

    Yamada, Nezu, Shimane, Hirata: "Molecular cloning of a novel vascular endothelial growth factor, VEGF-D." dans: Genomics, Vol. 42, Issue 3, pp. 483-8, (1997) (PubMed).

  • Antigène

    VEGFD (Figf) (C-Fos Induced Growth Factor (Vascular Endothelial Growth Factor D) (Figf))

    Autre désignation

    Vascular endothelial growth factor D

    Sujet

    C-fos induced growth factor (FIGF) (or vascular endothelial growth factor D, VEGF-D) is a vascular endothelial growth factor that in humans is encoded by the FIGF gene. The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. Analyzing by Northern blotting, Yamada et al. (1997) symbolized VEGFD, was expressed as a 2. 2-kb transcript with highest expression in lung, heart, small intestine, and fetal lung, and lower levels in skeletal muscle, colon, and pancreas. And Achen et al. (1998) concluded that VEGFD was most closely related to VEGFC by virtue of the presence of N- and C-terminal extensions that were not found in other VEGF family members. Stacker et al. (2001) showed that VEGFD can induce tumor angiogenesis through VEGFR2 and tumor lymphangiogenesis through VEGFR3, whereas VEGF, which does not activate VEGFR3, induces only tumor angiogenesis.

    Pathways

    Signalisation RTK
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