ELAVL1 anticorps
Aperçu rapide pour ELAVL1 anticorps (ABIN577055)
Antigène
Voir toutes ELAVL1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Greater than 95%
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Purification
- Purified IgG
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Pureté
- > 98 %
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Immunogène
- Synthetic Peptide
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Isotype
- IgG1
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Indications d'application
- Works on IHC at 1/2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1mg/ml
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Buffer
- PBS /glycerol
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Stock
- -20 °C
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: "ELAVL1a is an immunocompetent protein that protects zebrafish embryos from bacterial infection." dans: Communications biology, Vol. 4, Issue 1, pp. 251, (2021) (PubMed).
: "Elavl1a regulates zebrafish erythropoiesis via posttranscriptional control of gata1." dans: Blood, Vol. 123, Issue 9, pp. 1384-92, (2014) (PubMed).
: "Antagonistic function of the RNA-binding protein HuR and miR-200b in post-transcriptional regulation of vascular endothelial growth factor-A expression and angiogenesis." dans: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4908-21, (2013) (PubMed).
: "Stabilization of Dll1 mRNA by Elavl1/HuR in neuroepithelial cells undergoing mitosis." dans: Molecular biology of the cell, Vol. 22, Issue 8, pp. 1227-39, (2011) (PubMed).
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- ELAVL1 (ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 1 (Hu Antigen R) (ELAVL1))
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Autre désignation
- HuR
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Sujet
- HuR (also called Elavl-1 or HuA) is a protein that binds to specific AU-rich elements in a mRNA and thereby upregulates its expression. The protein contains three RRM type RNA binding domains. The first and second RNA binding domains interact with the AU-rich element. HuR is a member of a family of proteins called the elav-like proteins. The other members, HuD, HuC, and HEL-N1 are predominantly expressed in neurons. Monoclonal 19F12 was designed by CLONEGENE and was generated against a unique HuR peptide and does not react with HuD, HuC, or Hel-N1.
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Pathways
- AMPK Signaling
Antigène
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