ELAVL1
Reactivité: Humain, Souris, Rat
WB, IHC, ELISA, IF, ICC
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Titration of the HuR antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS pH 7.4 with 0.09 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Aliquot the HuR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
anticorps ELAV1, anticorps HUR, anticorps Hua, anticorps MelG, anticorps HuR, anticorps 2410055N02Rik, anticorps W91709, anticorps elra, anticorps fa25f08, anticorps fb59a02, anticorps fc60g02, anticorps hua, anticorps wu:fa25f08, anticorps wu:fb59a02, anticorps wu:fc60g02, anticorps zHuA, anticorps Elavl1, anticorps Xel-1, anticorps elav1, anticorps elrA, anticorps hur, anticorps melg, anticorps p36, anticorps ElrA, anticorps elavl1, anticorps elavl1-a, anticorps elavl1-b, anticorps ELAV like RNA binding protein 1, anticorps ELAV-like protein 1, anticorps ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R), anticorps ELAV like RNA binding protein 1a, anticorps ELAV like RNA binding protein 1 L homeolog, anticorps ELAV like RNA binding protein 1 S homeolog, anticorps ELAVL1, anticorps Elavl1, anticorps elav1, anticorps elavl1a, anticorps elavl1.L, anticorps elavl1.S
Sujet
ELAVL1/HuR is involved in 3'-UTR ARE-mediated MYC stabilization. It binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.