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Osteoprotegerin anticorps

TNFRSF11B Reactivité: Humain WB, EIA Hôte: Souris Monoclonal OPG-01 unconjugated
N° du produit ABIN114706
  • Antigène Voir toutes Osteoprotegerin (TNFRSF11B) Anticorps
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Reactivité
    • 61
    • 21
    • 18
    • 2
    • 2
    • 2
    • 2
    Humain
    Hôte
    • 50
    • 12
    • 2
    • 1
    Souris
    Clonalité
    • 54
    • 11
    Monoclonal
    Conjugué
    • 43
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Osteoprotegerin est non-conjugé
    Application
    • 49
    • 29
    • 26
    • 18
    • 11
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificité
    The antibody recognizes human Osteoprotegerin. Other species not tested.
    Purification
    Affinity chromatography on protein G
    Immunogène
    Recombinant human Osteoprotegerin (OPG Fc Chimera) produced in E. coli.
    Clone
    OPG-01
    Isotype
    IgG1
    Top Product
    Discover our top product TNFRSF11B Anticorps primaire
  • Indications d'application
    ELISA. Western Blot.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Restore with 0.1 mL of deionized water. Let the pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.
    Concentration
    1.0 mg/mL
    Buffer
    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2
    Conseil sur la manipulation
    Avoid repeated freezing and thawing. Do Not Freeze working dilutions.
    Stock
    -20 °C
    Stockage commentaire
    Stock solution or aliquots thereof can be kept frozen at -20 °C.
  • Antigène
    Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
    Autre désignation
    Osteoprotegerin / TNFRSF11B (TNFRSF11B Produits)
    Synonymes
    anticorps CD254, anticorps ODF, anticorps OPGL, anticorps OPTB2, anticorps RANKL, anticorps TRANCE, anticorps hRANKL2, anticorps sOdf, anticorps OCIF, anticorps OPG, anticorps TR1, anticorps Opg, anticorps ocif, anticorps opg, anticorps tr1, anticorps TNF superfamily member 11, anticorps TNF receptor superfamily member 11b, anticorps tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin), anticorps TNF receptor superfamily member 11B, anticorps tumor necrosis factor receptor superfamily member 11b S homeolog, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps TNFSF11, anticorps TNFRSF11B, anticorps Tnfrsf11b, anticorps tnfrsf11b.S
    Classe de substances
    Chemical
    Sujet
    Osteoprotegerin (OPG) or osteoclastogenesis inhibitory factor (OCIF) is a secretory glycoprotein belonging to TNF receptor superfamily. OPG consists of 401 amino acid residues, it has a molecular weight of 60 kDa as a monomer and 120 kDa as a disulfide-linked dimer and is produced in different tissues, e.g. bone, skin, liver, stomach, intestine and lung. Osteoprotegerin inhibits the recruitment, proliferation and activation of osteoclasts. Osteoclast formation activity may be monitored principally by determination of concentration ratio of osteoprotegerin ligand (OPGL)/OPG. Alteration of this ratio may be the cause of bone loss in many imbalances in bone metabolism such as osteoporosis, osteopetrosis, hypercalcemia, metastatic osteolytic lesions and rheumatic bone degradation.Synonyms: OCIF, OPG, Osteoclastogenesis inhibitory factor, Tumor necrosis factor receptor superfamily member 11B
    ID gène
    4982
    NCBI Accession
    NP_002537
    UniProt
    O00300
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