DZIP3 anticorps (DAZ Interacting Protein 3, Zinc Finger) (HRP)

Details for Product anti-DZIP3 Antibody No. ABIN1712040, Fournisseur: Connectez-vous pour afficher
Antigène
  • 2310047C04Rik
  • 2A-HUB
  • 6430549P11Rik
  • A230104G20
  • PPP1R66
  • UURF2
  • hRUL138
  • RGD1563278
  • DAZ interacting protein 3, zinc finger
  • DAZ interacting zinc finger protein 3
  • Dzip3
  • DZIP3
Reactivité
Humain, Souris, Rat (Rattus)
48
32
29
Hôte
Lapin
45
4
Clonalité
Polyclonal
Conjugué
Cet anticorp DZIP3 est conjugé à/à la HRP
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
26
22
13
9
9
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human DZIP3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Dzip3 (DZIP3 Antibody Extrait)
Sujet

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). DZIP3 (DAZ interacting protein 3, zinc finger), also known as UURF2 or hRUL138, is a 1,208 amino acid protein that localizes to the cytoplasm and contains one RING-type zinc finger. Expressed in a variety of tissues with highest expression in heart, skeletal muscle and kidney, DZIP3 functions as an E3 ubiquitin-protein ligase that accepts ubiquitin from an E2 ubiquitin-conjugating enzyme, thereby playing a role in signaling events throughout the cell. Multiple isoforms of DZIP3 exist due to alternative splicing events.

Synonyms: DAZ-interacting protein 3, E3 ubiquitin-protein ligase DZIP3, hRUL138, KIAA0675, RNA-binding ubiquitin ligase of 138 kDa, DZIP3_HUMAN.

ID gène 9666
Domaine de recherche Chromatin and Nuclear Signaling, Cell Cycle, Proteolysis / Ubiquitin
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months