AMHR2 anticorps (Anti-Mullerian Hormone Receptor, Type II) (HRP)

Details for Product anti-AMHR2 Antibody No. ABIN1712149, Fournisseur: Connectez-vous pour afficher
Antigène
  • AMHR
  • MISR2
  • MISRII
  • MRII
  • Misiir
  • Misrii
  • Mrii
  • anti-Mullerian hormone receptor, type II
  • anti-Mullerian hormone type 2 receptor
  • AMHR2
  • Amhr2
Reactivité
Humain, Souris, Rat (Rattus)
72
29
20
2
2
2
2
1
1
1
Hôte
Lapin
62
4
4
2
Clonalité
Polyclonal
Conjugué
Cet anticorp AMHR2 est conjugé à/à la HRP
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
52
27
13
7
6
6
3
3
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human MISRII/AMHR2
Isotype IgG
Purification Purified by Protein A.
Autre désignation Misrii/Amhr2 (AMHR2 Antibody Extrait)
Sujet

MISR II is a 573 amino acid protein encoded by the human gene AMHR2. MISR II belongs to the protein kinase superfamily, TKL Ser/Thr protein kinase family, TGFB receptor subfamily and contains one protein kinase domain. Upon ligand binding, MISR II forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. These type II receptors rylate and activate type I receptors which autophosphorylate, then bind and activate Smad transcriptional regulators. MISR II also acts as a receptor for anti-Muellerian hormone. Defects in AMHR2 are the cause of persistent Muellerian duct syndrome type 2 (PMDS-2). PMDS-2 is a form of male pseudo-hermaphroditism characterized by a failure of Muellerian duct regression in otherwise normal males.

Subcellular location: Extracellular

Synonyms: AMH type II receptor, AMHR2, AMHR2_HUMAN, Anti-Muellerian hormone type II receptor, Anti-Muellerian hormone type-2 receptor, MGC141312, MIS type II receptor, MISRII, MRII, Muellerian hormone type 2 receptor, Muellerian hormone type II receptor, Mullerian hormone receptor type II.

ID gène 269
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months