EYA4 anticorps (Eyes Absent Homolog 4 (Drosophila)) (HRP)

Details for Product anti-EYA4 Antibody No. ABIN1712264, Fournisseur: Connectez-vous pour afficher
Antigène
  • B130023L16Rik
  • CMD1J
  • DFNA10
  • eyes absent 4 homolog (Drosophila)
  • eyes absent homolog 4 (Drosophila)
  • Eya4
  • EYA4
Alternatives
anti-Humain EYA4 anticorps pour Western Blotting
Reactivité
Humain, Souris, Rat (Rattus)
66
22
18
6
5
3
2
2
2
2
Hôte
Lapin
51
16
Clonalité
Polyclonal
Conjugué
Cet anticorp EYA4 est conjugé à/à la HRP
4
4
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
37
29
22
18
17
13
4
3
2
1
Options
Fournisseur
Connectez-vous pour afficher
Supplier Product No.
Connectez-vous pour afficher
Request

Ce produit gratuit

Envoyez-nous votre proposition de validation. J'aimerais valider ce produit

Savoir plus

Immunogène KLH conjugated synthetic peptide derived from human EYA4
Isotype IgG
Purification Purified by Protein A.
Autre désignation Eya4 (EYA4 Antibody Extrait)
Sujet

A gene of chromosome 6q23 encodes the 640 amino acid protein, EYA4 (eyes absent) (1). EYA is one of four members of the eyes absent family (1). A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1). EYA4 is expressed in the craniofacial mesenchyme, the dermamyotome, and the limb (1). The conserved region in other EYA proteins interacts with SIX, DACH, and G-proteins, which regulate transcription in early embryonic development (1,2,3,4). SIX translocates EYA1-3 to the nucleus, and G-proteins can stop this interaction (3,4). Premature stop codon mutations in EYA4 cause postlingual, progressive autosomal dominant hearing loss in humans (2). This shows that EYA4 is also vital to the mature organ of Corti (2). EYA4 may cause oculo-dento-digital syndrome, based on its expression pattern and map postion (1).

Synonyms: CMD1J, Deafness, autosomal dominant 10, DFNA 10, DFNA10, dJ78N10.1 eyes absent Drosophila homolog 4, dJ78N10.1 eyes absent, EYA 4, eya4, EYA4_HUMAN, Eyes absent 4, Eyes absent homolog 4 Drosophila, Eyes absent homolog 4, HGNC:3522, OTTHUMP00000040267.

ID gène 2070
Pathways Sensory Perception of Sound
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months