L(3)mbt-Like 3 (Drosophila) (L3MBTL3) anticorps (HRP)

Détails pour le produit réf. ABIN1712357, Fournisseur: Connectez-vous pour afficher
Antigène
  • MBT-1
  • MBT1
  • RP11-73O6.1
  • AI481284
  • l(3)mbt-like 3 (Drosophila)
  • L3MBTL3
  • L3mbtl3
Reactivité
Humain, Souris, Rat (Rattus)
41
20
17
5
4
4
3
2
2
1
1
Hôte
Lapin
37
4
Clonalité
Polyclonal
Conjugué
HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
20
13
8
8
4
4
4
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human L3MBTL3
Isotype IgG
Purification Purified by Protein A.
Autre désignation L3mbtl3 (L3MBTL3 Antibody Extrait)
Sujet

Polycomb group (PcG) proteins are important for maintaining the transcriptionally repressed state of target genes and are thought to function via chromatin modification. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. PcG proteins are also required for normal maturation of myeloid progenitor cells. A putative PcG protein, L3MBTL3 (lethal(3)malignant brain tumor-like protein 3), also known as MBT-1 or KIAA1798, is a 780 amino acid protein containing three MBT repeats and one SAM (sterile alpha motif) domain. Localized to the nucleus, L3MBTL3 interacts with RING1B, another PcG protein that may be involved in the specification of anterior-posterior axis and cell proliferation in early development. L3MBTL3 exists as two isoforms produced by alternative splicing events.

Synonyms: Hl3mbt like protein, KIAA1798, l3mbt like 3 Drosophila, l3mbt like 3, L3mbt like 3 protein, Lethal3malignant brain tumor like 3 protein, MBT1, LMBL3_HUMAN.

ID gène 84456
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months