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Sorting Nexin 9 (SNX9) anticorps (HRP)

Détails pour le produit réf. ABIN1712388, Fournisseur: Connectez-vous pour afficher
Antigène
  • si:bz36d5.4
  • snx9
  • zgc:113455
  • MGC78823
  • SNX9
  • SDP1
  • SH3PX1
  • SH3PXD3A
  • WISP
  • 2700073N08Rik
  • sorting nexin 9a
  • sorting nexin 9
  • snx9a
  • SNX9
  • snx9
  • Snx9
Reactivité
Humain, Souris, Rat (Rattus)
82
31
27
15
13
2
1
1
1
1
Hôte
Lapin
36
30
16
Clonalité
Polyclonal
Conjugué
HRP
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
59
31
26
25
22
13
12
6
5
2
Options
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Immunogène KLH conjugated synthetic peptide derived from human SNX9
Isotype IgG
Purification Purified by Protein A.
Autre désignation Snx9/Sh3px1 (SNX9 Antibody Extrait)
Sujet

Involved in endocytosis and intracellular vesicle trafficking, both during interphase and at the end of mitosis. Required for efficient progress through mitosis and cytokinesis. Required for normal formation of the cleavage furrow at the end of mitosis. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.

Subcellular location: Cytoplasm, Cell membrane


Synonyms: SDP1, WISP, SH3PX1, SH3PXD3A, Sorting nexin-9, SH3 and PX domain-containing protein 1, Protein SDP1, SH3 and PX domain-containing protein 3A, SNX9
ID gène 51429
UniProt Q9Y5X1
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months