SUMF1 anticorps (Sulfatase Modifying Factor 1) (HRP)

Details for Product anti-SUMF1 Antibody No. ABIN1712396, Fournisseur: Connectez-vous pour afficher
Antigène
  • AAPA3037
  • FGE
  • AA543204
  • AI463102
  • AI851573
  • sulfatase modifying factor 1
  • SUMF1
  • Sumf1
Reactivité
Humain, Souris, Rat (Rattus)
59
25
20
6
6
5
4
3
3
2
2
2
1
Hôte
Lapin
44
15
Clonalité
Polyclonal
Conjugué
Cet anticorp SUMF1 est conjugé à/à la HRP
5
5
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
31
17
17
13
8
2
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human SUMF1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Sumf1 (SUMF1 Antibody Extrait)
Sujet

SUMF1 is a 374 amino acid alternatively spliced protein that localizes to the lumen of the endoplasmic reticulum and belongs to the sulfatase-modifying factor family. Expressed ubiquitously with highest expression in liver, kidney and pancreas, SUMF1 exists as either a monomer, a homodimer or a heterodimer (with SUMF2) and functions to oxidize sulfatase cysteine residues to an active FGIy residue, thereby playing an important role in sulfatase activity. Defects in the gene encoding SUMF1 are the cause of multiple sulfatase deficiency (MSD), a heterogeneous disorder characterized by metachromatic leukodystrophy, mucopolysaccharidosis, chondrodysplasia punctata, hydrocephalus, ichthyosis, neurologic deterioration and developmental delay.

Synonyms: MGC150436, AAPA3037, C alpha formylglycine generating enzyme 1, C-alpha-formylglycine-generating enzyme 1, FGE, FGly generating enzyme, MGC131853, Sulfatase modying factor 1 [Precursor], Sulfatase-modying factor 1, SUMF1, SUMF1_HUMAN, UNQ3037.

ID gène 285362
Domaine de recherche Stem Cells
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months