FOXH1 anticorps (Forkhead Box H1) (HRP)

Details for Product anti-FOXH1 Antibody No. ABIN1712522, Fournisseur: Connectez-vous pour afficher
Antigène
  • FOXH1
  • XFast-1
  • fast-1
  • fast1
  • foxh1a
  • xfast1
  • xfoxh1
  • FAST-1
  • FAST1
  • Fast1
  • Fast2
  • fast-2
  • SUR
  • fast
  • fe26b06
  • schmalspur
  • wu:fe26b06
  • wu:fi30c08
  • wu:fi32b01
  • forkhead box H1
  • FOXH1
  • foxh1
  • LOC100301631
  • Foxh1
Alternatives
anti-Humain FOXH1 anticorps pour Immunofluorescence (fixed cells)
Reactivité
Humain, Souris, Rat (Rattus)
52
40
29
2
2
2
2
1
1
1
1
1
Hôte
Lapin
58
2
Clonalité
Polyclonal
Conjugué
Cet anticorp FOXH1 est conjugé à/à la HRP
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
36
19
13
8
6
4
2
2
1
1
Options
Fournisseur
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Immunogène KLH conjugated synthetic peptide derived from human FOXH1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Foxh1 (FOXH1 Antibody Extrait)
Sujet

Xenopus winged-helix factor, xFAST-1 (forkhead activin signal transducer-1) is a transcription factor that forms a complex with the receptor-regulated Smad protein, Smad2, and directly binds to activin response elements on DNA (1,2). The human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states (3,4). FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4 (3,5). Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues (6,7). FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGß, and activin, indicating that these FAST proteins mediate TFGß, induced signal transduction (3).

Synonyms: FAST 1, Fast 2, Fast-1, Fast-2, FAST1, Fast2, Forkhead activin signal transducer 1, Forkhead activin signal transducer 2, Forkhead box H1, Forkhead box protein H1, FOX H1, FOXH 1, FOXH1, FOXH1_HUMAN, hFAST 1, hFAST-1, hFAST1, Human homolog of Xenopus forkhead activin signal transducer 1, TGF beta/Activin signal transducer FAST1.

ID gène 8928
Domaine de recherche Chromatin and Nuclear Signaling, Transcription Factors
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Indications d'application WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock 4 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months