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GDP Dissociation Inhibitor 1 (GDI1) anticorps (HRP)

Détails pour le produit réf. ABIN1712533, Fournisseur: Connectez-vous pour afficher
Antigène
  • 1A
  • GDIL
  • MRX41
  • MRX48
  • OPHN2
  • RABGD1A
  • RABGDIA
  • XAP-4
  • gdi2
  • GDI-1
  • GDIA
  • GDIalpha
  • GDP dissociation inhibitor 1
  • guanosine diphosphate (GDP) dissociation inhibitor 1
  • GDI1
  • gdi1
  • Gdi1
Reactivité
Humain, Souris, Rat (Rattus)
80
39
36
5
4
4
4
4
3
1
1
1
1
Hôte
Lapin
68
12
Clonalité
Polyclonal
Conjugué
HRP
4
4
3
3
3
3
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
63
38
15
13
6
5
2
2
1
Options
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Immunogène KLH conjugated synthetic peptide derived from human GDI1
Isotype IgG
Purification Purified by Protein A.
Autre désignation Gdi1 (GDI1 Antibody Extrait)
Sujet

Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).


Synonyms: 1A, FLJ41411, GDI-1, gdi1, GDIA_HUMAN, GDIL, GDP dissociation inhibitor 1, Guanosine diphosphate dissociation inhibitor 1, Mental retardation X-linked 41, Mental retardation X-linked 48, MRX41, MRX48, Oligophrenin 2, Oligophrenin-2, OPHN2, Protein XAP 4, Protein XAP-4, Protein XAP4, Rab GDI alpha, Rab GDP dissociation inhibitor alpha, RABGD1A, RABGDIA, XAP 4.
ID gène 2664
Domaine de recherche Signaling
Indications d'application WB(1:100-1000), IHC-P(1:100-500)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Agent conservateur Gentamicin sulfate
Précaution d'utilisation This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months