Protein C Light Chain (AA 131-230) anticorps (HRP)

N° du produit ABIN1712605

Détail du produit

Antigène: Protein C Light Chain

Épitope: AA 131-230

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: HRP

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Vitamin K-dependent protein C light chain

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Protein C Light Chain

Sujet:

Synonyms: Protein C, Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, EC 3.4.21.69, PC, PROC, PROC1, Vitamin K dependent protein C precursor, APC, EC 3.4.21.69, PC, proC, PROC_HUMAN, Protein C inactivator of coagulation factors Va and VIIIa, Vitamin K dependent protein C, Vitamin K-dependent protein C, Vitamin K-dependent protein C light chain.

Background: This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009].