Patched Domain Containing 2 (PTCHD2) anticorps (PE)

Détails pour le produit réf. ABIN1712719, Fournisseur: Connectez-vous pour afficher
Antigène
  • DISP3
  • G630052C06Rik
  • RNDEu-2
  • RGD1305820
  • patched domain containing 2
  • PTCHD2
  • ptchd2
  • Ptchd2
Reactivité
Humain, Souris, Rat (Rattus)
48
19
19
Hôte
Lapin
48
Clonalité
Polyclonal
Conjugué
PE
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
19
17
13
13
12
3
1
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Immunogène KLH conjugated synthetic peptide derived from human PTCHD2/DISP3
Isotype IgG
Purification Purified by Protein A.
Autre désignation Ptchd2/Disp3
Sujet

PTCHD2 is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22.

Subcellular location: Extracellular


Synonyms: DISP3, Dispatched, drosophila, homolog of, 3, G630052C06Rik, hCG_24779, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3, Ptchd2, PTHD2_HUMAN, RGD1305820, RND-type protein RNDEu-2, RNDEu-2, patched domain containing 2, RP23-157B15.1.
ID gène 57540
Indications d'application FCM(1:20-100)
Commentaires

Exitation/Emission: 480,565nm/578nm

Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at 4°C
Date de péremption 12 months