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CEA anticorps (Carcinoembryonic Antigen Gene Family)

Détail du produit anti-CEA anticorps No. ABIN1713338, Fournisseur: Connectez-vous pour afficher
Antigène
  • CEA
  • CEB
  • Ctsea
  • PSBG2
  • PSG1
  • carcinoembryonic antigen gene family
  • cathepsin E
  • pregnancy specific beta-1-glycoprotein 2
  • Cea
  • Ctse
  • PSG2
Reactivité
Humain
602
88
21
16
14
2
Hôte
Souris
499
102
14
1
1
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp CEA est non-conjugé
31
25
21
19
12
12
10
10
8
8
8
8
8
8
8
8
8
7
7
4
4
4
4
4
4
4
4
4
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
286
270
209
205
173
153
127
121
87
50
21
15
8
6
6
2
2
2
1
1
1
1
1
Options
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Immunogène KLH conjugated synthetic peptide derived from Human CEA/CEACAM5
Clone 3G7
Isotype IgG
Purification Purified by Protein G.
Autre désignation CEA (CEA Antibody Extrait)
Sujet

CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.


Synonyms: Carcino Embryonic Antigen CEA, CEACAM 5, CEACAM-5, Carcinoembryonic antigen, Carcinoembryonic antigen related cell adhesion molecule 5, CD66e, CD66e antigen, CEA, CEACAM5, DKFZp781M2392, Meconium antigen 100.
ID gène 1048
Domaine de recherche Cancer
Indications d'application WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Stock -20 °C
Stockage commentaire Store at -20°C
Date de péremption 12 months
Produit citée dans: Ren, Wu, Ju, Yan: "Target-Driven Triple-Binder Assembly of MNAzyme for Amplified Electrochemical Immunosensing of Protein Biomarker." dans: Analytical chemistry, Vol. 87, Issue 3, pp. 1694-700, 2015 (PubMed).