CBFA2T3 anticorps (N-Term)

N° du produit ABIN182912

Détail du produit anti-CBFA2T3 anticorps

Antigène: CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBFA2T3 est non-conjugé

Application: Western Blotting (WB)

Séquence: QPRSTPPSMP PPPPAASQGA TRPPSFTPHT LMNGSSHSPT AINGAPCTPN

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 85%, Human: 100%, Mouse: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CBFA2T3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CBFA2T3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 567 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CBFA2T3

Antigène: CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))

Autre désignation: CBFA2T3 (CBFA2T3 Produits)

Synonymes: anticorps A630044F12Rik, anticorps AI465270, anticorps AW229127, anticorps Cbfa2t3h, anticorps ETO-2, anticorps Eto2, anticorps MTGR2, anticorps MTG16a, anticorps MTG16b, anticorps ETO2, anticorps MTG16, anticorps ZMYND4, anticorps core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human), anticorps CBFA2/RUNX1 translocation partner 3, anticorps Cbfa2t3, anticorps CBFA2T3

Sujet: The t(16,21)(q24,q22) translocation is a rare but recurrent chromosomal abnormality associated with therapy-related myeloid malignancies. The translocation produces a chimeric gene made up of the 5'-region of the AML1 gene fused to the 3'-region of CBFA2T3. In addition, CBFA2T3 is a putative breast tumor suppressor.
Alias Symbols: ETO2, MTG16, MTGR2, ZMYND4
Protein Interaction Partner: Zbtb38, Zbtb4, ZBTB33, GMEB2, SEC24A, MATN2, ZBTB47, UBC, RUNX1, TAL1, TRIM33, SIN3B, NCOR1, HDAC3, CBFA2T3, CBFA2T2, HDAC1, PRKAR2A, RUNX1T1, LDB1, TCF3, HDAC8, HDAC6, HDAC2,
Protein Size: 567

Poids moléculaire: 62 kDa

ID gène: 863

NCBI Accession: NM_175931, NP_787127

UniProt: O75082