HLA-E anticorps (APC)

N° du produit ABIN2658335

Détail du produit anti-HLA-E anticorps (APC)

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HLA-E est conjugé à/à la APC

Application: Intracellular Flow Cytometry (ICFC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: 3D12

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur HLA-E

Antigène: HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))

Autre désignation: HLA-E (HLA-E Produits)

Synonymes: anticorps EA1.2, anticorps EA2.1, anticorps HLA-6.2, anticorps MHC, anticorps QA1, anticorps major histocompatibility complex, class I, E, anticorps HLA-E, anticorps PATR-E

Sujet: HLA-E is a non-classical MHC class I (MHC-Ib) molecule. It is characterized by limited polymorphism and ubiquitous expression. HLA-E, as other MHC-I molecules, is heterodimerized with β2-microglobulin. HLA-E interacts with CD94/NKG2 receptor to regulate NK cell cytolysis activities.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process