PHOX2A anticorps (N-Term)

N° du produit ABIN2777426

Détail du produit anti-PHOX2A anticorps

Antigène: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHOX2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: AVPYKFFPEP SGLHEKRKQR RIRTTFTSAQ LKELERVFAE THYPDIYTRE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Attributs du produit: This is a rabbit polyclonal antibody against PHOX2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PHOX2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 284 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PHOX2A

Antigène: PHOX2A (Paired-Like Homeobox 2a (PHOX2A))

Autre désignation: PHOX2A (PHOX2A Produits)

Synonymes: anticorps ARIX, anticorps CFEOM2, anticorps FEOM2, anticorps NCAM2, anticorps PMX2A, anticorps Arix, anticorps Phox2, anticorps Pmx2, anticorps Pmx2a, anticorps arix, anticorps sou, anticorps zgc:77364, anticorps phox2, anticorps xphox2a, anticorps paired like homeobox 2a, anticorps paired-like homeobox 2a, anticorps paired like homeobox 2a S homeolog, anticorps PHOX2A, anticorps Phox2a, anticorps phox2a, anticorps phox2a.S

Sujet: PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene.The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARIX, CFEOM2, FEOM2, MGC52227, NCAM2, PMX2A
Protein Interaction Partner: SP1, PHOX2A, HAND2, PRKACA, ATF6B, CREBBP, JUN,
Protein Size: 284

Poids moléculaire: 30 kDa

ID gène: 401

NCBI Accession: NM_005169, NP_005160

UniProt: O14813