Estrogen Receptor alpha anticorps (Middle Region)
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- Antigène Voir toutes Estrogen Receptor alpha (ESR1) Anticorps
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Épitope
- Middle Region
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Reactivité
- Humain, Rat, Boeuf (Vache), Porc, Chien, Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Estrogen Receptor alpha est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- LLEMLDAHRL HAPTSRGGAS VEETDQSHLA TAGSTSSHSL QKYYITGEAE
- Homologie
- Cow: 83%, Dog: 79%, Human: 100%, Pig: 79%, Rat: 86%, Sheep: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against ESR1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human ESR1
- Top Product
- Discover our top product ESR1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 595 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Autre désignation
- ESR1 (ESR1 Produits)
- Synonymes
- anticorps LOC398734, anticorps AA420328, anticorps AU041214, anticorps ER-alpha, anticorps ER[a], anticorps ERa, anticorps ERalpha, anticorps ESR, anticorps Estr, anticorps Estra, anticorps Nr3a1, anticorps NR3A1, anticorps eralpha, anticorps zfER[a], anticorps ER, anticorps ESRA, anticorps ESTRR, anticorps Era, anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps Esr, anticorps RNESTROR, anticorps ERALPHA, anticorps er, anticorps esr, anticorps nr3a1, anticorps XER, anticorps era, anticorps esra, anticorps ERbeta, anticorps xesr-1, anticorps xlERalpha1, anticorps xlERalpha2, anticorps ESR1, anticorps estrogen receptor 1 L homeolog, anticorps estrogen receptor 1 (alpha), anticorps estrogen receptor 1, anticorps A kinase (PRKA) anchor protein 12b, anticorps esr1.L, anticorps Esr1, anticorps ESR1, anticorps esr1, anticorps akap12b
- Sujet
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Hairy/enhancer of split-related proteins, such as HEY1, are basic helix-loop-helix (bHLH) transcription factors implicated in cell fate decision and boundary formation. HEY genes are direct transcriptional targets of the Notch signaling pathways in Drosophila and vertebrates. This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.
Alias Symbols: DKFZp686N23123, ER, ESR, ESRA, Era, NR3A1
Protein Interaction Partner: SRC, DDX5, POLR2C, POLR2B, POLR2A, MSH2, TTC5, KAT5, NCOA2, BRCA1, MED24, UBC, PSMB9, MED1, POLR2L, POLR2K, POLR2J, POLR2I, POLR2H, POLR2G, POLR2F, POLR2E, POLR2D, ASCC1, TRRAP, PHB2, NCOR1, NCOA1, PIK3CA, IGF1R, HDAC1, NSD1, WIPI1, ESR1, ZNF131, RANBP9,
Protein Size: 595 - Poids moléculaire
- 66 kDa
- ID gène
- 2099
- NCBI Accession
- NM_000125, NP_000116
- UniProt
- P03372
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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