FTL anticorps (Middle Region)

N° du produit ABIN2785638

Détail du produit anti-FTL anticorps

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Chien, Porc, Lapin, Cobaye, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FTL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: ALLDLHALGS ARTDPHLCDF LETHFLDEEV KLIKKMGDHL TNLHRLGGPE

Homologie: Cow: 79%, Dog: 93%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%, Sheep: 77%

Attributs du produit: This is a rabbit polyclonal antibody against FTL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human FTL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 175 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FTL

Antigène: FTL (Ferritin, Light Polypeptide (FTL))

Autre désignation: FTL (FTL Produits)

Synonymes: anticorps NBIA3, anticorps apoferritin, anticorps ferritin, anticorps fhc, anticorps fth, anticorps fth1, anticorps fthl6, anticorps ftn-2, anticorps pig15, anticorps plif, anticorps FT, anticorps Ftl, anticorps Ftl-1, anticorps L-ferritin, anticorps FTL, anticorps Ftl1, anticorps FTL2, anticorps FTD, anticorps ferritin light chain, anticorps ferritin, heavy polypeptide 1 L homeolog, anticorps ferritin light polypeptide 1, anticorps ferritin, light polypeptide, anticorps ferritin light-chain, anticorps ferritin light chain 1, anticorps FTL, anticorps fth1.L, anticorps Ftl1, anticorps CpipJ_CPIJ004069, anticorps Ftl

Sujet: FTL is the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene encodes the light subunit of the ferritin protein. Ferritin is the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyperferritinemia-cataract syndrome. This gene has multiple pseudogenes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC71996, NBIA3
Protein Interaction Partner: USHBP1, SDCBP, MYOG, KPNA3, FTL, FTH1, CEP250, CEP57, AURKA, PACSIN2, COL4A3BP, IGSF8, NAMPT, SMAD9, HTT, VKORC1, PPP1CC, POLR2D, HSPD1, HSP90AB3P, EIF4G1, TOX4, MYOC, UBC, CLEC4G, RAP2A, PIK3CA, GRB2, UCHL5, MPHOSPH6, TAF10, MPP6, IGDCC3, MAP3K12, KNG1,
Protein Size: 175

Poids moléculaire: 20 kDa

ID gène: 2512

NCBI Accession: NM_000146, NP_000137

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis