IRF6 anticorps (C-Term)
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- Antigène Voir toutes IRF6 Anticorps
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Chien, Lapin, Cheval, Boeuf (Vache), Cobaye, Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IRF6 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- FLSDLIAHQK GQIEKQPPFE IYLCFGEEWP DGKPLERKLI LVQVIPVVAR
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against IRF6. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human IRF6
- Top Product
- Discover our top product IRF6 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 591 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- IRF6 (Interferon Regulatory Factor 6 (IRF6))
- Autre désignation
- IRF6 (IRF6 Produits)
- Synonymes
- anticorps IRF6, anticorps lps, anticorps pit, anticorps pps, anticorps vws, anticorps ofc6, anticorps xIRF-6, anticorps DKFZp469E012, anticorps LPS, anticorps OFC6, anticorps PIT, anticorps PPS, anticorps PPS1, anticorps VWS, anticorps VWS1, anticorps zgc:63500, anticorps AI876454, anticorps E230028I05Rik, anticorps mirf6, anticorps interferon regulatory factor 6, anticorps interferon regulatory factor 6 S homeolog, anticorps IRF6, anticorps irf6, anticorps irf6.S, anticorps Irf6
- Sujet
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IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. Mutations in its gene can cause van der Woude syndrome and popliteal pterygium syndrome. This protein is involved in palate formation.The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Alias Symbols: LPS, OFC6, PIT, PPS, VWS, VWS1
Protein Interaction Partner: HHV8GK18_gp81, UBC, BNC2, IRF5, IRF8, ZBTB3, RFX3, TLX2, LBP,
Protein Size: 591 - Poids moléculaire
- 65 kDa
- ID gène
- 3664
- NCBI Accession
- NM_004661, NP_006138
- UniProt
- O14896
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