NR1I3 anticorps (N-Term)

N° du produit ABIN310698

Détail du produit anti-NR1I3 anticorps

Antigène: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Boeuf (Vache), Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NR1I3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MASREDELRN CVVCGDQATG YHFNALTCEG CKGFFRRTVS KSIGPTCPFA

Homologie: Cow: 90%, Dog: 92%, Guinea Pig: 79%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against NR1I3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NR1I3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 348 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur NR1I3

Antigène: NR1I3 (Nuclear Receptor Subfamily 1, Group I, Member 3 (NR1I3))

Autre désignation: NR1I3 (NR1I3 Produits)

Synonymes: anticorps AA209988, anticorps AI551208, anticorps CAR, anticorps CAR-beta, anticorps Care2, anticorps ESTM32, anticorps MB67, anticorps CAR1, anticorps CXR, anticorps nuclear receptor subfamily 1 group I member 3, anticorps nuclear receptor subfamily 1, group I, member 3, anticorps NR1I3, anticorps Nr1i3

Sujet: NR1I3 mediates the induction of transcription of cytochrome P450 (CYP) genes by phenobarbital (PB) and PB-type inducers. NR1I3 activation induces hepatic expression of detoxification enzymes and transporters and increases liver size. NR1I3 can also regulate both liver homeostasis and tumorigenesis in response to xenobiotic stresses.
Alias Symbols: CAR, CAR1, MB67, MGC150433, MGC97144, MGC97209
Protein Interaction Partner: HSP90AA1, RXRA, CHD9, SNX13, SNRPD3, IGH, PSMC5, PSMC4, EIF3I, SRC, MAP4, FTH1, HNF4A, NR0B2, PPARGC1A, MED1, NCOA1, POU1F1,
Protein Size: 348

Poids moléculaire: 39 kDa

ID gène: 9970

NCBI Accession: NM_005122, NP_005113

UniProt: Q5VTW5

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway