ING1 anticorps (C-Term)

N° du produit ABIN311312

Détail du produit anti-ING1 anticorps

Antigène: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Poisson zèbre (Danio rerio), Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ING1 est non-conjugé

Application: Western Blotting (WB)

Séquence: EKKAKTSKKK KRSKAKAERE ASPADLPIDP NEPTYCLCNQ VSYGEMIGCD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against ING1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ING1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 279 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ING1

Antigène: ING1 (Inhibitor of Growth Family, Member 1 (ING1))

Autre désignation: ING1 (ING1 Produits)

Synonymes: anticorps p24ING1c, anticorps p33, anticorps p33ING1, anticorps p33ING1b, anticorps p47, anticorps p47ING1a, anticorps p33ING1c, anticorps zgc:136918, anticorps ING1, anticorps 2610028J21Rik, anticorps AA407184, anticorps AI875420, anticorps mING1h, anticorps p33Ing1, anticorps p37Ing1b, anticorps xing1, anticorps inhibitor of growth family member 1, anticorps inhibitor of growth family, member 1, anticorps inhibitor of growth family member 1 S homeolog, anticorps ING1, anticorps Ing1, anticorps ing1, anticorps ing1.S

Sujet: ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis. The encoded protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of this gene have been detected in various cancers. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: p24ING1c, p33, p33ING1, p33ING1b, p47, p47ING1a
Protein Interaction Partner: SIRT1, SIRT2, UBC, HDAC1, KIAA0101, PCNA, RBP1, RBBP7, RBBP4, HDAC2, BRMS1L, SIN3A, BRMS1, SAP30, ELAVL1, SMURF1, COPS2, NQO1, HIST2H3C, MRGBP, YWHAZ, YWHAH, YWHAG, YWHAE, YWHAB, KPNA2, KPNB1, YWHAQ, SFN, ESR1, LMNA, CDKN2A, TP53, KAT2B, DMAP1, EP300, HHT
Protein Size: 279

Poids moléculaire: 32 kDa

ID gène: 3621

NCBI Accession: NM_198219, NP_937862

UniProt: Q5T9H0

Pathways: Protein targeting to Nucleus, Autophagy