SMARCA4 anticorps (C-Term)

N° du produit ABIN343708

Cet anticorps Souris Monoclonal détecte spécifiquement SMARCA4 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SMARCA4 anticorps (C-Term) (ABIN343708)

Antigène: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMARCA4 est non-conjugé

Application: Western Blotting (WB)

Clone: BRG-01

Détail du produit anti-SMARCA4 anticorps

Épitope: C-Term

Fonction: Anti-BRG1 Purified

Réactivité croisée (Details): Human, Other not determined

Attributs du produit: The antibody BRG-01 recognizes an epitope within C-terminal part of human Brg1, a 205 kDa catalytic subunit of SWI2/SNF2-family chromatin-remodeling complexes.

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Bacterially produced GST-fused protein representing 242 C-terminal amino acids of human Brg1.

Isotype: IgG2a

Information d'application

Indications d'application: Western blotting: Recommended dilution: 10 μg/mL, positive control: HEK293 cells.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur SMARCA4

Antigène: SMARCA4 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 4 (SMARCA4))

Autre désignation: BRG1

Sujet: SWI/SNF related, matrix associated, actin dependen,Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.,CSS4, SMARCA4, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB

ID gène: 6597

UniProt: P51532

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance