anti-Choline Acetyltransferase anticorps

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	Antigène:	Choline Acetyltransferase
	Clonalité:	Polyclonal
	Application:	Western Blotting (WB), Immunohistochemistry (IHC)
	Reactivité:	Chicken, Guinea Pig, Human, Mouse (Murine), Primates, Rat (Rattus)
	Hôte:	Rabbit
	Quantité:	100 µl
	Prix:	265,00 $ (Plus frais de livraison $25 et TVA, Invoice in EUR)
	Numéro du produit:	ABIN361420
	Disponibilité:	Envoi sous 5 à 7 jours ouvrables

Antigène	Choline Acetyltransferase
Reactivité	Chicken, Guinea Pig, Human, Mouse (Murine), Primates, Rat (Rattus)
Clonalité	Polyclonal
Description	Choline acetyltransferase is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. It is therefore found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome (Holt et al. 1999). Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects (Karson et al 1993). It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function (Baskin et al. 1999). .Anti-Choline Acetyltransferase Western blot of rat brain lysate showing specific immunolabeling of the ~68/70k ChAT
Hôte	Rabbit
Specificité	Specific for the ~ 68/70 k choline acetyltransferase protein

Application	Western Blotting (WB), Immunohistochemistry (IHC)
Indications d'application	Recommended Dilution: WB: 1:1000 IHC: 1:100 Quality Control: Western blots performed on each lot.
Purification	Neat serum
Stock	Store at -20 °C, stable for 1 year
Domaine de recherche	Neurology
Restrictions	For Research Use only