Choline Acetyltransferase anticorps (AA 331-630)
Aperçu rapide pour Choline Acetyltransferase anticorps (AA 331-630) (ABIN3016135)
Antigène
Voir toutes Choline Acetyltransferase (CHAT) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 331-630
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Séquence
- VLVQCTEHLL KHMTQSSRKL IRADSVSELP APRRLRWKCS PEIQGHLASS AEKLQRIVKN LDFIVYKFDN YGKTFIKKQK CSPDAFIQVA LQLAFYRLHR RLVPTYESAS IRRFQEGRVD NIRSATPEAL AFVRAVTDHK AAVPASEKLL LLKDAIRAQT AYTVMAITGM AIDNHLLALR ELARAMCKEL PEMFMDETYL MSNRFVLSTS QVPTTTEMFC CYGPVVPNGY GACYNPQPET ILFCISSFHS CKETSSSKFA KAVEESLIDM RDLCSLLPPT ESKPLATKEK ATRPSQGHQP
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogène
- Recombinant fusion protein containing a sequence corresponding to amino acids 331-630 of human CHAT (NP_001136401.1).
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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Autre désignation
- CHAT
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Sujet
- This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.,CHAT,CHOACTASE,CMS1A,CMS1A2,CMS6,Neuroscience,Cell Type Marker,Neuron marker,CHAT
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Poids moléculaire
- 70 kDa/74 kDa/82 kDa
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ID gène
- 1103
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UniProt
- P28329
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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