CACNA1C anticorps (AA 1507-1733)

N° du produit ABIN361759

Cet anticorps Souris Monoclonal détecte spécifiquement CACNA1C dans IHC, WB, IP, IF, ICC et AA. Il présente une réactivité avec des échantillons de Lapin.

Aperçu rapide pour CACNA1C anticorps (AA 1507-1733) (ABIN361759)

Antigène: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Reactivité: Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CACNA1C est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Clone: S57

Détail du produit anti-CACNA1C anticorps

Épitope: AA 1507-1733

Specificité: Detects ~240 kDa (varies with cell background due to glycosylation).

Réactivité croisée: Hamster, Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• IP (1:200)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN361759 was sufficient for detection of Cav1.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur CACNA1C

Antigène: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Autre désignation: Cav1.2

Sujet: Cav1.2 is a cardiac L-type calcium channel, and is important for excitation and contraction of the heart (1). It may be associated with a variant of Long QT syndrome called Timothy's syndrome (2, 3) and also with Brugada syndrome. Some references also suggest it is related to bipolar disease as well (3).

ID gène: 100101555

NCBI Accession: NP_001129994

UniProt: P15381

Pathways: Hormone Transport, Carbohydrate Homeostasis