CACNA1C anticorps (AA 1507-1733) (HRP)

N° du produit ABIN2485658

Détail du produit anti-CACNA1C anticorps (HRP)

Antigène: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Épitope: AA 1507-1733

Reactivité: Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CACNA1C est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)

Specificité: Detects ~240 kDa (varies with cell background due to glycosylation).

Réactivité croisée: Hamster, Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2

Clone: S57

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:1000)
• IHC (1:1000)
• ICC/IF (1:100)
• IP (1:200)
• optimal dilutions for assays should be determined by the user.

Commentaires:

1 μg/ml of ABIN2485658 was sufficient for detection of Cav1.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur CACNA1C

Antigène: CACNA1C (Calcium Channel, Voltage-Dependent, L Type, alpha 1C Subunit (CACNA1C))

Autre désignation: Cav1.2 (CACNA1C Produits)

Synonymes: anticorps CACH2, anticorps CACN2, anticorps CACNL1A1, anticorps CCHL1A1, anticorps CaV1.2, anticorps LQT8, anticorps TS, anticorps Cav1.2, anticorps Cchl1a1, anticorps MBC, anticorps MELC-CC, anticorps RATIVS302, anticorps isl, anticorps C-LTCC, anticorps CHCACHA1C, anticorps ICA, anticorps cav1.2, anticorps ca(v)1.2, anticorps CAV1.2, anticorps BCR, anticorps rbc, anticorps calcium voltage-gated channel subunit alpha1 C, anticorps calcium channel, voltage-dependent, L type, alpha 1C subunit, anticorps voltage-dependent L-type calcium channel subunit alpha-1C, anticorps calcium channel, voltage-dependent, L type, alpha 1C subunit S homeolog, anticorps Red blood cell count, anticorps RNA, 7SL, cytoplasmic 263, pseudogene, anticorps CACNA1C, anticorps Cacna1c, anticorps cacna1c, anticorps LOC100442085, anticorps cacna1c.S, anticorps RBC, anticorps RN7SL263P

Sujet: Cav1.2 is a cardiac L-type calcium channel, and is important for excitation and contraction of the heart (1). It may be associated with a variant of Long QT syndrome called Timothy's syndrome (2, 3) and also with Brugada syndrome. Some references also suggest it is related to bipolar disease as well (3).

ID gène: 100101555

NCBI Accession: NP_001129994

UniProt: P15381

Pathways: Hormone Transport, Carbohydrate Homeostasis