CDK2 anticorps (pThr160)
Aperçu rapide pour CDK2 anticorps (pThr160) (ABIN362119)
Antigène
Voir toutes CDK2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- pThr160
-
Specificité
- The antibody detects endogenous level of CDK2 only when phosphorylated at threonine 160.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
-
Immunogène
- Peptide sequence around phosphorylation site of pThr160 (T-Y-T (p) -H-E) derived from Human CDK2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
-
Autre désignation
- CDK2
-
Sujet
- Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.
-
Poids moléculaire
- 34 kDa
-
NCBI Accession
- NP_001789
-
UniProt
- P24941
-
Pathways
- Signalisation PI3K-Akt, Cycle Cellulaire, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
Antigène
-