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MEK1 + MEK2 anticorps (pSer217, pSer221)

Cet anticorps anti-MEK1 + MEK2 Polyclonal Lapin (ABIN362235) détecte spécifiquement MEK1 + MEK2 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.
N° du produit ABIN362235
268,40 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 10 à 14 jours ouvrables

Aperçu rapide pour MEK1 + MEK2 anticorps (pSer217, pSer221) (ABIN362235)

Antigène

MEK1 + MEK2

Reactivité

  • 31
  • 23
  • 23
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 30
  • 1
Lapin

Clonalité

  • 29
  • 2
Polyclonal

Conjugué

  • 24
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MEK1 + MEK2 est non-conjugé

Application

  • 23
  • 14
  • 10
  • 5
  • 5
  • 3
  • 2
  • 1
Immunohistochemistry (IHC)
  • Épitope

    • 12
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer217, pSer221

    Specificité

    The antibody detects endogenous level of MEK1/MEK2 only when phosphorylated at serine 217/221.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.

    Immunogène

    Peptide sequence around phosphorylation site of pSer217, 221 (I-D-S (p) -M-A) derived from Human MEK1, MEK2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

    Isotype

    IgG
  • Indications d'application

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Antigène

    MEK1 + MEK2

    Autre désignation

    MEK1/MEK2

    Sujet

    Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.

    Poids moléculaire

    45 kDa

    UniProt

    Q02750
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