MPP7 anticorps (N-Term)

N° du produit ABIN406339

Détail du produit anti-MPP7 anticorps

Antigène: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Lapin, Boeuf (Vache), Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MPP7 est non-conjugé

Application: Western Blotting (WB)

Séquence: MPALSTGSGS DTGLYELLAA LPAQLQPHVD SQEDLTFLWD MFGEKSLHSL

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MPP7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MPP7

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 576 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-MPP7 (ABIN406339)

Stucke, Timmerman, Vandekerckhove, Gevaert, Hall: "The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation." dans: Molecular biology of the cell, Vol. 18, Issue 5, pp. 1744-55, (2007) (PubMed).

Détails sur MPP7

Antigène: MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))

Autre désignation: MPP7 (MPP7 Produits)

Synonymes: anticorps 1110068J02Rik, anticorps 2810038M04Rik, anticorps 5430426E14Rik, anticorps AI415104, anticorps Gm955, anticorps dlg3, anticorps hmp, anticorps membrane palmitoylated protein 7, anticorps membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7), anticorps membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7), anticorps MPP7, anticorps Mpp7, anticorps mpp7a

Sujet: MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).[supplied by OMIM].
Alias Symbols: FLJ32798, RP11-218D6.5
Protein Interaction Partner: AMOT, Wwtr1, Yap1, UBC,
Protein Size: 576

Poids moléculaire: 65 kDa

ID gène: 143098

NCBI Accession: NM_173496, NP_775767

UniProt: Q5T2T1

Pathways: Cell-Cell Junction Organization