MAPK8IP1 anticorps

N° du produit ABIN4904305

Détail du produit anti-MAPK8IP1 anticorps

Antigène: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAPK8IP1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.

Purification: Affinity purification

Immunogène: Recombinant protein of human MAPK8IP1.

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C.

Détails sur MAPK8IP1

Antigène: MAPK8IP1 (Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1))

Autre désignation: MAPK8IP1 (MAPK8IP1 Produits)

Synonymes: anticorps IB1, anticorps JIP-1, anticorps Jip1, anticorps Prkm8ip, anticorps Skip, anticorps mjip-2a, anticorps JIP1, anticorps Jip-1, anticorps Mapk8ip, anticorps PRKM8IP, anticorps mitogen-activated protein kinase 8 interacting protein 1, anticorps MAPK8IP1, anticorps Mapk8ip1

ID gène: 9479

UniProt: Q9UQF2