CDC16 anticorps (N-Term)

N° du produit ABIN499301

Détail du produit anti-CDC16 anticorps

Antigène: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDC16 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: APC6 antibody was raised against an 18 amino acid peptide near the amino terminus of human APC6.

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: APC6 antibody can be used for detection of APC6 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur CDC16

Antigène: CDC16 (Cell Division Cycle 16 Homolog (S. Cerevisiae) (CDC16))

Autre désignation: CDC16 / APC6 (CDC16 Produits)

Synonymes: anticorps zgc:123264, anticorps F9K20.19, anticorps F9K20_19, anticorps anaphase promoting complex 6, anticorps 2700071J12Rik, anticorps 2810431D22Rik, anticorps APC6, anticorps ANAPC6, anticorps CUT9, anticorps cell division cycle 16, anticorps cell division cycle 16 L homeolog, anticorps cell division cycle 16 homolog (S. cerevisiae), anticorps cell division cycle protein 16 homolog, anticorps anaphase promoting complex 6, anticorps CDC16 cell division cycle 16, anticorps CDC16, anticorps cdc16.L, anticorps cdc16, anticorps LOC100434328, anticorps APC6, anticorps Cdc16

Sujet: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC6 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC6, it has been shown to interact with and is stabilized by CDC26 through an intermolecular TPR mimic composed of one helix from each protein.Synonyms: ANAPC6, Anaphase-promoting complex subunit 6, CDC16Hs, Cell division cycle protein 16 homolog, Cyclosome subunit 6

ID gène: 8881

NCBI Accession: NP_003894

UniProt: Q13042

Pathways: Regulation of Actin Filament Polymerization