VARS anticorps (Middle Region)

N° du produit ABIN502716

Détail du produit anti-VARS anticorps

Antigène: VARS (Valyl-tRNA Synthetase (VARS))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cheval, Lapin, Chien, Cobaye, Poisson zèbre (Danio rerio), Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VARS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VFDEFVDMDF GTGAVKITPA HDQNDYEVGQ RHGLEAISIM DSRGALINVP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against VARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human VARS

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 1264 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-VARS (ABIN502716)

Duarte, Videira: "Defective valyl-tRNA synthetase hampers the mitochondrial respiratory chain in Neurospora crassa." dans: The Biochemical journal, Vol. 448, Issue 3, pp. 297-306, (2012) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Détails sur VARS

Antigène: VARS (Valyl-tRNA Synthetase (VARS))

Autre désignation: VARS (VARS Produits)

Synonymes: anticorps G7A, anticorps VARS1, anticorps VARS2, anticorps VARS, anticorps Bat6, anticorps D17H6S56E, anticorps G7a, anticorps Vars2, anticorps vars1, anticorps vars2, anticorps CHUNP6879, anticorps im:7137378, anticorps wu:fb07a11, anticorps wu:fb07d10, anticorps TrsVal, anticorps BEST:LD45671, anticorps CG4062, anticorps Dmel\\CG4062, anticorps VRS, anticorps ValRS, anticorps l(2)03531, anticorps l(2)rI255, anticorps ld45671, anticorps ECK4251, anticorps JW4215, anticorps val-act, anticorps T5E21.11, anticorps T5E21_11, anticorps TWIN 2, anticorps VALRS, anticorps VALYL TRNA SYNTHETASE, anticorps valyl-tRNA synthetase, anticorps Valyl-tRNA synthetase, anticorps valyl-tRNA synthetase S homeolog, anticorps hypothetical protein, anticorps valyl-tRNA synthetase 2, mitochondrial, anticorps valyl-tRNA synthetase / valine-tRNA ligase (VALRS), anticorps VARS, anticorps Vars, anticorps vars, anticorps ValRS, anticorps vars.S, anticorps MW0078, anticorps Pnap_3169, anticorps valS, anticorps Fnod_0343, anticorps Cyan7425_1070, anticorps Tola_0553, anticorps Slip_0680, anticorps Astex_3136, anticorps ML5_3395, anticorps VARS2, anticorps TWN2

Sujet: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. VARS belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: G7A, VARS2, VARS1
Protein Interaction Partner: CALCOCO2, SUMO2, SART3, STAU1, UBC, EED, CCT4, KNTC1, AIMP1, CCT3, QARS, EEF1G, EEF1D, EEF1B2, FBXO6, YWHAQ, MAPK11, VCAM1, ITGA4, FN1, LARS, CAD, UBD, SHC1, CUL3, CDK2, CHD7, CACNA1A, ATG101, OTUD5, DMWD, EEF1A1, EEF1A2, TRAF6, TFE3, HLA-B, EPB41,
Protein Size: 1264

Poids moléculaire: 140 kDa

ID gène: 7407

NCBI Accession: NM_006295, NP_006286

UniProt: P26640