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Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (N-Term) anticorps

Détails pour le produit réf. ABIN503085, Fournisseur: Connectez-vous pour afficher Nouveau
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Antigène
Synonymes GDAP1L1, MGC146673, dJ881L22.1, dJ995J12.1.1, Gdap1l
Épitope
N-Term
(3), (1), (1)
Reactivité
Boeuf (Vache), Chien, Humain, Souris, Rat (Rattus), Poisson zèbre (Danio rerio)
(19), (7), (6)
Hôte
Lapin
(11), (8)
Clonalité
Polyclonal
Application
Transfer Western (WB)
(17), (8), (6), (5), (3)
Pubmed 1 référence disponible
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Quantité 50 μg
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Destination France ( )
Disponibilité Envoi sous 6 à 8 jours ouvrables
Immunogène Synthetic peptide directed towards the N terminal of human GDAP1L1
Blocking Peptide Blocking peptide for this product available: ABIN977349
Séquence ERDVSLPQSE HKEPWFMRLN LGEEVPVIIH RDNIISDYDQ IIDYVERTFT
Homologie Bovine : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 70 %
Attributs du produit This is a rabbit polyclonal antibody against GDAP1L1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Autre désignation GDAP1L1 (GDAP1L1 Antibody Extrait)
Sujet The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. GDAP1L1 is similar in sequence to the human GDAP1 protein.The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein.
Poids moléculaire 42 kDa
ID gène 78997
NCBI Accession NP_076939, NM_024034
UniProt Q96MZ0
Indications d'application Optimal working dilutions should be determined experimentally by the investigator.
Commentaires

Antigen size: 367 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Conseil sur la manipulation Avoid repeated freeze-thaw cycles.
Stock -20 °C
Stockage commentaire For longer periods of storage, store at -20 °C
Supplier Images
Transfer Western (WB) image for anti-Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (N-Term) anticorps (ABIN503085) anti-Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (N-Term) antibody
Reference: Background Deloukas, Matthews, Ashurst et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." dans: Nature, Vol. 414, Issue 6866, pp. 865-71, 2002 (PubMed).

N° du produit ABIN503085
358,51 €
Plus frais de livraison 40,00 € et TVA

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