ERI2 anticorps (Middle Region)

N° du produit ABIN952142

Détail du produit anti-ERI2 anticorps

Antigène: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Épitope: AA 443-472, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERI2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human EXOD1 (Center).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 443-472 amino acids from the Central region of Human EXOD1 Genename: ERI2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ERI2

Antigène: ERI2 (EXOD1) (ERI1 Exoribonuclease Family Member 2 (EXOD1))

Autre désignation: EXOD1 (EXOD1 Produits)

Synonymes: anticorps exod1, anticorps EXOD1, anticorps Exod1, anticorps 4933424N09Rik, anticorps mKIAA1504, anticorps eri2, anticorps ERI1 exoribonuclease family member 2 L homeolog, anticorps ERI1 exoribonuclease family member 2, anticorps exoribonuclease 2, anticorps eri2.L, anticorps ERI2, anticorps Eri2, anticorps eri2

Sujet: EXOD1 (Exonuclease domain-containing protein 1), also known as ERI2 (ERI1 exoribonuclease 2), is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.Synonyms: Exonuclease domain-containing protein 1, KIAA1504, MGC16943

Poids moléculaire: 77401 Da

ID gène: 112479

NCBI Accession: NP_001136197