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gamma-Glutamyltransferase Light Chain 2 (GGTLC2) (AA 140-169), (Middle Region) anticorps

Détails pour le produit réf. ABIN952511, Fournisseur: Connectez-vous pour afficher
Antigène
  • GGTL4
Épitope
AA 140-169, Middle Region
15
13
9
1
Reactivité
Humain
31
Hôte
Lapin
31
Clonalité
Polyclonal
Conjugué
Inconjugué
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
19
16
14
14
11
5
Fournisseur
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Supplier Product No.
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Images

Immunogène KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of human GGTLC2
Isotype Ig
Specificité This antibody recognizes Human GGTLC2 (Center).
Purification Protein A column, followed by peptide affinity purification
Autre désignation GGTLC2 (GGTLC2 Antibody Extrait)
Sujet Gamma-glutamyltransferase-1 (GGT1, MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM].Synonyms: GGTL4, Gamma-glutamyltransferase light chain 2
Poids moléculaire 23661 Da
ID gène 91227
NCBI Accession NP_954578
Pathways
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-gamma-Glutamyltransferase Light Chain 2 (GGTLC2) (AA 140-169), (Middle Region) anticorps (ABIN952511) Flow cytometric analysis of U251 cells using GGTLC2 Antibody (Center) Cat.-No AP51833...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-gamma-Glutamyltransferase Light Chain 2 (GGTLC2) (AA 140-169), (Middle Region) anticorps (ABIN952511) Immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tiss...
Western Blotting (WB) image for anti-gamma-Glutamyltransferase Light Chain 2 (GGTLC2) (AA 140-169), (Middle Region) anticorps (ABIN952511) Western blot analysis of GGTLC2 Antibody (Center) in U251 cell line lysates (35ug/lan...
Reference: Background Heisterkamp, Groffen, Warburton et al.: "The human gamma-glutamyltransferase gene family." dans: Human genetics, Vol. 123, Issue 4, pp. 321-32, 2008 (PubMed).

Dunham, Shimizu, Roe et al.: "The DNA sequence of human chromosome 22. ..." dans: Nature, Vol. 402, Issue 6761, pp. 489-95, 1999 (PubMed).

Kawasaki, Minoshima, Nakato et al.: "One-megabase sequence analysis of the human immunoglobulin lambda gene locus." dans: Genome research, Vol. 7, Issue 3, pp. 250-61, 1997 (PubMed).

Leh, Courtay, Gerardin et al.: "Cloning and expression of a novel type (III) of human gamma-glutamyltransferase truncated mRNA." dans: FEBS letters, Vol. 394, Issue 3, pp. 258-62, 1996 (PubMed).