SNX15 anticorps (C-Term)

N° du produit ABIN954886

Détail du produit anti-SNX15 anticorps

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Épitope: AA 222-251, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX15 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects human SNX15 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region ( between 222-251aa) of human SNX15.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SNX15

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Autre désignation: Sorting Nexin-15 (SNX15) (SNX15 Produits)

Synonymes: anticorps SNX15, anticorps hsaf001435, anticorps snx15, anticorps MGC154249, anticorps HSAF001435, anticorps 1500032B08Rik, anticorps E130013C21Rik, anticorps sorting nexin 15, anticorps sorting nexin 15 S homeolog, anticorps SNX15, anticorps snx15.S, anticorps snx15, anticorps Snx15

Sujet: The SNX15 gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms.

ID gène: 29907

NCBI Accession: NP_037438