BTG1 anticorps (N-Term)

N° du produit ABIN965706

Détail du produit anti-BTG1 anticorps

Antigène: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BTG1 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human BTG1(B-cell translocation gene 1 protein)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur BTG1

Antigène: BTG1 (B-Cell Translocation Gene 1, Anti-Proliferative (BTG1))

Autre désignation: BTG1 (BTG1 Produits)

Synonymes: anticorps btg1, anticorps AI426953, anticorps AW546738, anticorps BTG anti-proliferation factor 1, anticorps BTG1 protein, anticorps B-cell translocation gene 1, anticorps B cell translocation gene 1, anti-proliferative, anticorps BTG1, anticorps CpipJ_CPIJ001938, anticorps btg1, anticorps Btg1

Sujet: BTG1(B-cell translocation gene 1 protein) is an anti-proliferative protein. Its expression is associated with the early G1 phase of the cell cycle. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. BTG1 expression is maximal in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. GTG1 negatively regulates cell proliferation. BTG1 is a novel important coactivator involved in the regulation of myoblast differentiation. BTG1 may play an important role in the process of angiogenesis. Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system. The C-terminal regions are necessary and sufficient to control the stabilities of BTG1, BTG2, Tob, and Tob2 proteins.

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development