STX8 anticorps (AA 57-164)

N° du produit ABIN968489

Détail du produit anti-STX8 anticorps

Antigène: STX8 (Syntaxin 8 (STX8))

Épitope: AA 57-164

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STX8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain, Chien, Rat (Rattus)

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Mouse Syntaxin 8 aa. 57-164

Clone: 48-Syntaxin 8

Isotype: IgG2a

Information d'application

Commentaires:

Related Products: ABIN967389, ABIN968536

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-STX8 (ABIN968489)

Steegmaier, Yang, Yoo, Huang, Shen, Yu, Luo, Scheller: "Three novel proteins of the syntaxin/SNAP-25 family." dans: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).

Thoreau, Bergès, Callebaut, Guillier-Gencik, Gressin, Bernheim, Karst, Mornon, Kitzis, Chomel: "Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)." dans: Biochemical and biophysical research communications, Vol. 257, Issue 2, pp. 577-83, (1999) (PubMed).

Détails sur STX8

Antigène: STX8 (Syntaxin 8 (STX8))

Autre désignation: Syntaxin 8 (STX8 Produits)

Synonymes: anticorps CG4109, anticorps Dm Syx8, anticorps DmSyx8, anticorps Dmel\\CG4109, anticorps SYX8, anticorps Syx, anticorps zgc:64079, anticorps syntaxin-8, anticorps STX8, anticorps GB11192, anticorps MGC116467, anticorps DDBDRAFT_0217663, anticorps DDBDRAFT_0231533, anticorps DDB_0217663, anticorps DDB_0231533, anticorps CARB, anticorps 0610007H08Rik, anticorps 1110002H11Rik, anticorps 4930571E13Rik, anticorps Syntaxin 8, anticorps syntaxin 8, anticorps syntaxin-8, anticorps syntaxin 8 S homeolog, anticorps Syx8, anticorps stx8, anticorps STX8, anticorps LOC552098, anticorps stx8.S, anticorps syn8A, anticorps Stx8

Sujet: Eukaryotic protein trafficking involves the packaging of molecules into membranous vesicles that bud from a donor compartment, travel to a specific destination, fuse, and release their components into an acceptor compartment. Recognition between vesicle and acceptor membrane is mediated by the pairing of the integral membrane SNARE proteins. The stable interaction between vesicle proteins (v-SNAREs) and target proteins (t-SNAREs) juxtaposes the membranes and results in an activated docking state and/or membrane fusion. The syntaxin protein family contains a number of members that serve as functional t-SNAREs. One member of this family, syntaxin 8, has two coiled-coil domains, one in the N-terminus and one toward the C-terminus. The C-terminal domain is homologous to a similar domain in syntaxin 6 and is predicted to interact in the formation of SNARE complexes, while a hydrophobic domain in the C-terminus may be involved in membrane anchoring. Syntaxin-8 is ubiquitously expressed, but is present at high levels in the heart and localizes specifically to the ER. Thus, syntaxin-8 is a t-SNARE that is thought to be involved in the early secretory pathway of many different cell types.

Poids moléculaire: 27 kDa

Pathways: Synaptic Vesicle Exocytosis