anti-Humain FGFR4 anticorps pour Immunocytochemistry

Recommended FGFR4 Antibody (fourni par: Connectez-vous pour afficher )

Antigène
Fibroblast Growth Factor Receptor 4 (FGFR4) Anticorps
  • FGFR4
  • XFGFR-4
  • XFGFR-4a
  • cd334
  • fgfr-4
  • jtk2
  • tkf
  • xfgfr4
  • CD334
  • JTK2
  • TKF
  • Fgfr-4
  • etID309818.21
  • wu:fc13h10
  • zgc:111935
  • fgfr-4c
  • fgfr4
  • fibroblast growth factor receptor 4
  • FGFR4
  • fgfr4
  • Fgfr4
  • fgfr4-b
Reactivité
Humain
207
56
45
3
3
Hôte
Souris
127
68
27
1
Clonalité
Monoclonal
Conjugué
Cet anticorp FGFR4 est non-conjugé
8
8
7
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
155
96
55
48
35
29
13
9
8
6
4
3
2
2
1
1
Options
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N° du produit ABIN969140
$ 393.80
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Fournisseur Clonality References Details
26.375908 ABIN4899673 CyTOF FACS ICC IHC WB Rat IgG2a AA 22-369 Connectez-vous pour afficher 240929
1 ABIN2869400 ELISA ICC WB Mouse IgG1 Connectez-vous pour afficher 7H1 2
1 ABIN4311563 ELISA ICC IF WB Mouse IgG1 Connectez-vous pour afficher 7H1
1 ABIN4311567 ICC IF IHC IHC (p) Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN4311568 ICC IF IHC IHC (p) WB Rabbit IgG Connectez-vous pour afficher Polyclonal
1 ABIN5646530 CyTOF FACS ICC IHC WB Rat IgG2a AA 22-369 Connectez-vous pour afficher 240929
1 ABIN1858881 ICC IHC IP WB Rabbit IgG AA 168-369 Connectez-vous pour afficher Polyclonal

General

Antigène Fibroblast Growth Factor Receptor 4 (FGFR4) Anticorps
Reactivité Humain
(207), (56), (45), (3), (3)
Hôte Souris
(127), (68), (27), (1)
Clonalité (Clone)
Monoclonal   ( )
Conjugué Cet anticorp FGFR4 est non-conjugé
(8), (8), (7), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Immunocytochemistry (ICC), ELISA, Western Blotting (WB)
(155), (96), (55), (48), (35), (29), (13), (9), (8), (6), (4), (3), (2), (2), (1), (1)
Pubmed 2 références disponible
Fournisseur Connectez-vous pour afficher

Détail du produit anti-FGFR4 anticorps

Détail du antigène FGFR4 Information d'application Stockage References for anti-FGFR4 antibody (ABIN969140) Images
Purification Ascites
Immunogène Purified recombinant extracellular fragment of human FGFR4 fused with hIgGFc tag expressed in HEK293 cell line.
Clone 7H1
Isotype IgG1

Détail du antigène FGFR4

Détail du produit anti-FGFR4 anticorps Information d'application Stockage References for anti-FGFR4 antibody (ABIN969140) Images Haut de la page
Antigène
Autre désignation FGFR4 (FGFR4 Antibody Extrait)
Sujet FGFR4: fibroblast growth factor receptor 4. Entrez Protein NP_002002. It is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. The genomic organization of this gene, compared to members 1-3, encompasses 18 exons rather than 19 or 20. Although alternative splicing has been observed, there is no evidence that the C-terminal half of the IgIII domain of this protein varies between three alternate forms, as indicated for members 1-3. This particular family member preferentially binds acidic fibroblast growth factor and, although its specific function is unknown, it is overexpressed in gynecological tumor samples, suggesting a role in breast and ovarian tumorigenesis.
Poids moléculaire 87.9 kDa
ID gène 2264
HGNC 2264
Domaine de recherche Cancer, Growth Factors, Angiogenesis, Receptors
Pathways Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding

Information d'application

Détail du produit anti-FGFR4 anticorps Détail du antigène FGFR4 Stockage References for anti-FGFR4 antibody (ABIN969140) Images Haut de la page
Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000
Restrictions For Research Use only

Stockage

Détail du produit anti-FGFR4 anticorps Détail du antigène FGFR4 Information d'application References for anti-FGFR4 antibody (ABIN969140) Images Haut de la page
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage

References for anti-FGFR4 antibody (ABIN969140)

Détail du produit anti-FGFR4 anticorps Détail du antigène FGFR4 Information d'application Stockage Images Haut de la page
Produit citée dans:

Huang, Yang, Luo, Jin, Wang, McKeehan: "FGFR4 prevents hyperlipidemia and insulin resistance but underlies high-fat diet induced fatty liver." dans: Diabetes, Vol. 56, Issue 10, pp. 2501-10, 2007

Streit, Mestel, Schmidt, Ullrich, Berking: "FGFR4 Arg388 allele correlates with tumour thickness and FGFR4 protein expression with survival of melanoma patients." dans: British journal of cancer, Vol. 94, Issue 12, pp. 1879-86, 2006

Images

Détail du produit anti-FGFR4 anticorps Détail du antigène FGFR4 Information d'application Stockage References for anti-FGFR4 antibody (ABIN969140) Haut de la page
Supplier Images
Immunocytochemistry (ICC) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibody (ABIN969140) Figure 1: Confocal immunofluorescence analysis of methanol-fixed HEK293 cells trasfec...
Western Blotting (WB) image for anti-Fibroblast Growth Factor Receptor 4 (FGFR4) antibody (ABIN969140) Figure 2: Western blot analysis using FGFR4 mouse mAb against extracellular domain of...