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Aperçu des produits pour anti-Phospholipase C gamma 2 (PLCG2) Anticorps

Full name:
anti-Phospholipase C gamma 2 Anticorps (PLCG2)
Chez www.anticorps-enligne.fr sont 269 Phospholipase C gamma 2 (PLCG2) Anticorps de 24 de différents fournisseurs disponibles. De plus, nous expédions Phospholipase C gamma 2 Kits (21) et Phospholipase C gamma 2 Protéines (4) et beaucoup plus de produits pour cette protéine. Un total de 312 Phospholipase C gamma 2 produits sont actuellement listés.
Synonymes:
APLAID, FCAS3, Plcg-2, PLCgamma2

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anti-Mouse (Murine) Phospholipase C gamma 2 Anticorps:

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anti-Phospholipase C gamma 2 Anticorps mieux référencés

  1. Human Polyclonal Phospholipase C gamma 2 Primary Antibody pour IF, WB - ABIN197402 : Kim, Sekiya, Poulin, Bae, Rhee: Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2. dans Molecular and cellular biology 2004 (PubMed)
    Show all 4 references for ABIN197402

  2. Human Polyclonal Phospholipase C gamma 2 Primary Antibody pour IF, IHC (p) - ABIN319401 : Smrcka, Hepler, Brown, Sternweis: Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq. dans Science (New York, N.Y.) 1991 (PubMed)
    Show all 4 references for ABIN319401

  3. Human Polyclonal Phospholipase C gamma 2 Primary Antibody pour IF, WB - ABIN196906 : Humphries, Dangelmaier, Sommer, Kipp, Kato, Griffith, Bakman, Turk, Daniel, Rawlings: Tec kinases mediate sustained calcium influx via site-specific tyrosine phosphorylation of the phospholipase Cgamma Src homology 2-Src homology 3 linker. dans The Journal of biological chemistry 2004 (PubMed)
    Show all 4 references for ABIN196906

  4. Human Polyclonal Phospholipase C gamma 2 Primary Antibody pour IHC (p) - ABIN319283 : Mattaj: A binding consensus: RNA-protein interactions in splicing, snRNPs, and sex. dans Cell 1989 (PubMed)
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  5. Human Polyclonal Phospholipase C gamma 2 Primary Antibody pour IF (p), IHC (p) - ABIN700375 : Diaz-Flores, Goldschmidt, Depeille, Ng, Akutagawa, Krisman, Crone, Burgess, Williams, Houseman, Shokat, Sampath, Bollag, Roose, Braun, Shannon: PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. dans Science signaling 2013 (PubMed)

  6. Human Polyclonal Phospholipase C gamma 2 Primary Antibody pour IHC, ELISA - ABIN1531237 : Martin, Han, Gordon, Terry, Prabhakar, She, Xie, Hellsten, Chan, Altherr, Couronne, Aerts, Bajorek, Black, Blumer, Branscomb, Brown, Bruno, Buckingham, Callen, Campbell, Campbell, Campbell, Caoile et al.: The sequence and analysis of duplication-rich human chromosome 16. ... dans Nature 2004 (PubMed)

Plus d’anticorps contre Phospholipase C gamma 2 partenaires d’interaction

Mouse (Murine) Phospholipase C gamma 2 (PLCG2) interaction partners

  1. Results show that mice with the mutated Plcg2 gene were less prone to transformation into MALT lymphomas as a result of elevated Treg numbers, and decrease of pro-inflammatory cytokines.

  2. PLCgamma2 in clear cells plays an essential role in luminal expansion of the epididymis during the prepubertal period in mice

  3. platelet activation through GPVI (Montrer GP6 Anticorps) and alphaIIbbeta3 utilizes PLCgamma2 because PLCgamma1 (Montrer PLCG1 Anticorps) levels are insufficient to support responsiveness, but that PLCgamma1 (Montrer PLCG1 Anticorps) can restore responsiveness if expressed at levels normally achieved by PLCgamma2.

  4. amarogentin prevents platelet activation through the inhibition of PLC (Montrer HSPG2 Anticorps) gamma2-PKC (Montrer PKC Anticorps) cascade and MAPK (Montrer MAPK1 Anticorps) pathway

  5. PLCgamma2 and protein kinase C (Montrer PKC Anticorps) are important upstream signals that regulate myelopoiesis through cytokines.

  6. inflammatory osteolysis can be abrogated by treatment with a molecule composed of the tandem SH2 (Montrer MYO15 Anticorps) domains of PLCgamma2.

  7. down-regulation of PLCgamma2-beta-catenin (Montrer CTNNB1 Anticorps) pathway occurs in mice and humans and leads to myeloid-derived suppressor cells-mediated tumor expansion.

  8. a novel role of the PLCgamma2-IP(3)-Ca(2 (Montrer CA2 Anticorps)+) cascade in the LPS (Montrer TLR4 Anticorps)-induced innate immune response pathway where release of intracellular Ca(2 (Montrer CA2 Anticorps)+) mediates TLR4 (Montrer TLR4 Anticorps) trafficking and subsequent activation of IRF3 (Montrer IRF3 Anticorps).

  9. VapB (Montrer VAPB Anticorps) positively regulates RANKL (Montrer TNFSF11 Anticorps)-mediated osteoclastogenesis via PLCgamma2-Ca(2 (Montrer CA2 Anticorps)+)-NFAT (Montrer NFATC1 Anticorps) signaling

  10. PLCgamma2 deficiency impairs Dectin-2 (Montrer CLEC6A Anticorps)-induced NF-kappaB (Montrer NFKB1 Anticorps) and MAPK (Montrer MAPK1 Anticorps) activation in response to fungal infection

Human Phospholipase C gamma 2 (PLCG2) interaction partners

  1. Data show that phospholipase Cgamma2 (PLCgamma2) is strongly expressed in B cell non-Hodgkin lymphoma and especially in a large subset of Diffuse large B-cell lymphoma (DLBCL).

  2. Characterization of the effect of missense point-mutation at R665W in PLCG2 on signaling mechanisms of ibrutinib resistance in chronic lymphocytic leukemia cells.

  3. amarogentin prevents platelet activation through the inhibition of PLC (Montrer HSPG2 Anticorps) gamma2-PKC (Montrer PRRT2 Anticorps) cascade and MAPK (Montrer MAPK1 Anticorps) pathway

  4. PLCG2 missense mutation is a risk factor in the development of steroid sensitive nephrotic syndrome in childhood.

  5. The autoinhibitory C-terminal SH2 domain of phospholipase C (Montrer PLC Anticorps)-gamma2 stabilizes B cell receptor signalosome assembly.

  6. The relationship between upstream tyrosine kinase (Montrer TXK Anticorps) SYK (Montrer SYK Anticorps) and its target, PLCgamma2, is maximally predictive and sufficient to distinguish chronic lymphocytic leukemia from healthy controls.

  7. Single-nucleotide polymorphisms in PLCG2 gene is associated with breast cancer risk after menopausal hormone replacement therapy.

  8. identified three distinct mutations in PLCgamma2 in two patients resistant to ibrutinib

  9. early Ca(2 (Montrer CA2 Anticorps)+) fluxing provides feed-forward signal amplification by promoting anchoring of the PLCgamma2 C2 domain to phospho-SLP65 (Montrer BLNK Anticorps).

  10. BANK1 (Montrer BANK1 Anticorps) and BLK (Montrer BLK Anticorps) have roles in B-cell signaling through phospholipase C gamma 2

Phospholipase C gamma 2 (PLCG2) profil antigène

Antigen Summary

The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane.

Alternative names and synonyms associated with Phospholipase C gamma 2 (PLCG2)

  • phospholipase C, gamma 2 (Plcg2) anticorps
  • phospholipase C, gamma 2 (phosphatidylinositol-specific) (PLCG2) anticorps
  • phospholipase C, gamma 2 (phosphatidylinositol-specific) (Plcg2) anticorps
  • APLAID anticorps
  • FCAS3 anticorps
  • Plcg-2 anticorps
  • PLCgamma2 anticorps

Protein level used designations for PLCG2

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 , 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 , PLC-gamma-2 , phosphoinositide phospholipase C-gamma-2 , phospholipase C-gamma-2 , PLC-IV , phosphoinositide phospholipase C , phospholipase C-IV , phosphatidylinositol-specific phospholipase C

GENE ID SPECIES
234779 Mus musculus
29337 Rattus norvegicus
5336 Homo sapiens
489692 Canis lupus familiaris
100518663 Sus scrofa
281988 Bos taurus
415805 Gallus gallus
100726796 Cavia porcellus
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