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Aperçu des produits pour anti-PTK2B (PTK2B) Anticorps

Full name:
anti-PTK2B Protein tyrosine Kinase 2 beta Anticorps (PTK2B)
Chez www.anticorps-enligne.fr sont 243 PTK2B Protein tyrosine Kinase 2 beta (PTK2B) Anticorps de 24 de différents fournisseurs disponibles. De plus, nous expédions PTK2B Kits (20) et PTK2B Protéines (11) et beaucoup plus de produits pour cette protéine. Un total de 292 PTK2B produits sont actuellement listés.
Synonymes:
Akt, CADTK, CAKB, CAKbeta, E430023O05Rik, FADK2, FAK2, PKB, PKB/Akt, PKBalpha, PTK, Pyk2, Rac, Raftk

Réactivités les plus populaires pour anti-PTK2B (PTK2B) Anticorps

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anti-Rat (Rattus) PTK2B Anticorps:

anti-Mouse (Murine) PTK2B Anticorps:

anti-Human PTK2B Anticorps:

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anti-PTK2B Anticorps mieux référencés

  1. Human Polyclonal PTK2B Primary Antibody pour IF, IHC (p) - ABIN196952 : Gluck: Acid sensing in renal epithelial cells. dans The Journal of clinical investigation 2004 (PubMed)
    Show all 5 references for ABIN196952

  2. Human Monoclonal PTK2B Primary Antibody pour IHC, ELISA - ABIN1724705 : Dylla, Deyle, Theunissen, Padurean, Verfaillie: Integrin engagement-induced inhibition of human myelopoiesis is mediated by proline-rich tyrosine kinase 2 gene products. dans Experimental hematology 2004 (PubMed)
    Show all 3 references for ABIN1724705

  3. Human Polyclonal PTK2B Primary Antibody pour IHC, ELISA - ABIN1532112 : Lev, Moreno, Martinez, Canoll, Peles, Musacchio, Plowman, Rudy, Schlessinger: Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions. dans Nature 1995 (PubMed)
    Show all 2 references for ABIN1532112

  4. Human Polyclonal PTK2B Primary Antibody pour ELISA, WB - ABIN1533144 : Herzog, Nicholl, Hort, Sutherland, Shine: Molecular cloning and assignment of FAK2, a novel human focal adhesion kinase, to 8p11.2-p22 by nonisotopic in situ hybridization. dans Genomics 1997 (PubMed)
    Show all 2 references for ABIN1533144

  5. Human Polyclonal PTK2B Primary Antibody pour IF, IHC (p) - ABIN197440 : Benzing, Gerke, Höpker, Hildebrandt, Kim, Walz: Nephrocystin interacts with Pyk2, p130(Cas), and tensin and triggers phosphorylation of Pyk2. dans Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Show all 2 references for ABIN197440

  6. Human Polyclonal PTK2B Primary Antibody pour IF (p), IHC (p) - ABIN745763 : Cao, Zheng, Wang, Wang, Li, Li, Lai, Wang, Qin: Src blockage by siRNA inhibits VEGF-induced vascular hyperpemeability and osteoclast activity - an in vitro mechanism study for preventing destructive repair of osteonecrosis. dans Bone 2015 (PubMed)

  7. Cow (Bovine) Polyclonal PTK2B Primary Antibody pour WB - ABIN2779800 : Ling, Sheng, Braun: The calcium-dependent activity of large-conductance, calcium-activated K+ channels is enhanced by Pyk2- and Hck-induced tyrosine phosphorylation. dans American journal of physiology. Cell physiology 2004 (PubMed)

Plus d’anticorps contre PTK2B partenaires d’interaction

Mouse (Murine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. A cell-culture study using an inhibitor of estrogen receptors and an in vivo experiment with ovariectomized mice suggested that the estrogenic activity of 8-PN contributed to recovery from disuse muscle atrophy through activation of an Akt (Montrer AKT1 Anticorps) phosphorylation pathway. These data strongly suggest that 8-PN is a naturally occurring compound that could be used as a nutritional supplement to aid recovery from disuse muscle atroph

  2. Analysis of the successful model also elucidates two dynamical motifs: neutralization of a negative regulator, which characterizes how Akt (Montrer AKT1 Anticorps) indirectly activates mTORC1, and seesaw enzyme regulation, which describes how activated and inhibited states of mTORC1 are controlled in concert to produce a nonlinear, ultrasensitive response

  3. Data show that Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) and MAPK (Montrer MAPK1 Anticorps) pathways were activated in ovine pulmonary adenocarcinoma (OPA) lung and envelope (Env (Montrer ERVW-1 Anticorps)) of Jaagsiekte sheep retrovirus (JSRV) transfected NIH 3T3 cells.

  4. Results suggest that SC79 compound activates Akt (Montrer AKT1 Anticorps)-Nrf2 (Montrer NFE2L2 Anticorps) signaling to protect osteoblasts from dexamethasone (Dex).

  5. In conclusion, we have identified that ARL15 acts as an insulin (Montrer INS Anticorps)-sensitizing effector molecule to upregulate the phosphorylation of members of the canonical IR/IRS1 (Montrer IRS1 Anticorps)/PDPK1 (Montrer PDPK1 Anticorps)/AKT (Montrer AKT1 Anticorps) insulin (Montrer INS Anticorps) pathway by interacting with its GAP ASAP2 (Montrer ASAP2 Anticorps) and activating PDPK1 (Montrer PDPK1 Anticorps). This research may provide new insights into GTPase (Montrer RACGAP1 Anticorps)-mediated insulin (Montrer INS Anticorps) signalling regulation and facilitate the development of new pharmacotherapeutic targets for insulin (Montrer INS Anticorps) sensitizati

  6. Taken together, our findings imply that KLF15 possesses potential anti-hypertrophic and anti-fibrotic functions, possibly via regulation of cell death pathways and the inhibition of Akt/mTOR axis. KLF15 may constitute an efficient candidate drug for the treatment of heart failure and other cardiovascular diseases.

  7. Menin (Montrer MEN1 Anticorps) binds on the promoter of Inhbb (Montrer INHBB Anticorps) gene where it favours the recruitment of Ezh2 (Montrer EZH2 Anticorps) via an indirect mechanism involving Akt (Montrer AKT1 Anticorps)-phosphorylation.

  8. A role of AKT (Montrer AKT1 Anticorps) in the regulatory T cell differentiation process. TGF-beta (Montrer TGFB1 Anticorps) induces the phosphorylation of Akt (Montrer AKT1 Anticorps) in CD4 (Montrer CD4 Anticorps)+ T cells.

  9. 4-PBA reverses autophagic dysfunction and improves insulin (Montrer INS Anticorps) sensitivity in adipose tissue of obese mice via Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps) signaling partly, which could be regarded as novel opportunities for treatment of insulin (Montrer INS Anticorps) resistance.

  10. These studies reveal a novel mechanism in which CYP2J2 (Montrer CYP2J2 Anticorps) and epoxyeicosatrienoic acids enhanced Akt1 (Montrer AKT1 Anticorps) nuclear translocation through interaction with AMPKalpha2beta2gamma1 and protect against cardiac hypertrophy.

Human PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. We demonstrated trophoblast cytoprotection by intervention with supraphysiological concentrations of relaxin, a process in part mediated through the PI3-kinase (Montrer PIK3CA Anticorps)-Akt/PKB (Montrer AKT1 Anticorps) cell survival pathway. These results provide further rationale for clinical investigation of relaxin as a potential therapeutic in preeclampsia.

  2. PTK2B polymorphism (rs28834970) could modify the risk of late-onset Alzheimer's disease (LOAD), and PTK2B polymorphism (rs28834970) and APOE may interact to increase LOAD risk in a Han Chinese population.

  3. Studies suggest that PYK2 is a common downstream effector of ErbB (Montrer EGFR Anticorps) and IL8 (Montrer IL8 Anticorps) receptors, and that PYK2 integrates their signaling pathways through a positive feedback loop to potentiate breast cancer invasion.

  4. Pyk2 is a key downstream signaling molecules of CCR7 (Montrer CCR7 Anticorps) in SCCHN, which promotes SCCHN tumorigenesis and progression.

  5. Phosphoproteomic analysis identifies FAK2 as a potential therapeutic target for tamoxifen resistance in breast cancer.

  6. Pyk2-focal adhesion targeting domain interacts with and binds to leupaxin (Montrer LPXN Anticorps).

  7. Src (Montrer SRC Anticorps) has a role in priming Pyk2 (but not FAK (Montrer PTK2 Anticorps)) phosphorylation and subsequent activation downstream of integrins

  8. Data strongly suggest that chemokine-stimulated associations between Vav1, SLP-76, and ADAP facilitate Rac1 activation and alpha4beta1-mediated adhesion, whereas Pyk2 opposes this adhesion by limiting Rac1 activation.

  9. FAK (Montrer PTK2 Anticorps) and PYK2 functioned redundantly to promote the Wnt (Montrer WNT2 Anticorps)/beta-catenin (Montrer CTNNB1 Anticorps) pathway by phosphorylating GSK3beta (Montrer GSK3b Anticorps)(Y216) to reinforce pathway output-beta-catenin (Montrer CTNNB1 Anticorps) accumulation and intestinal tumorigenesis.

  10. This study identified Pyk2 as a cellular component required for the intracellular trafficking of HPV16 during infection.

Cow (Bovine) PTK2B Protein tyrosine Kinase 2 beta (PTK2B) interaction partners

  1. Ptk2b activation may play a key role in the signaling responses in ECs under hemodynamic influence [proline-rich tyrosine kinase 2]

PTK2B profil antigène

Antigen Summary

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

Alternative names and synonyms associated with PTK2B

  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) anticorps
  • thymoma viral proto-oncogene 1 (Akt1) anticorps
  • protein tyrosine kinase 2 beta (PTK2B) anticorps
  • protein tyrosine kinase 2 beta (Ptk2b) anticorps
  • PTK2 protein tyrosine kinase 2 beta (Ptk2b) anticorps
  • PTK2B protein tyrosine kinase 2 beta (PTK2B) anticorps
  • Akt anticorps
  • CADTK anticorps
  • CAKB anticorps
  • CAKbeta anticorps
  • E430023O05Rik anticorps
  • FADK2 anticorps
  • FAK2 anticorps
  • PKB anticorps
  • PKB/Akt anticorps
  • PKBalpha anticorps
  • PTK anticorps
  • Pyk2 anticorps
  • Rac anticorps
  • Raftk anticorps

Protein level used designations for PTK2B

AKT1 kinase , PKB alpha , RAC protein kinase alpha RAC-PK alpha , RAC-PK-alpha , RAC-alpha serine/threonine-protein kinase , murine thymoma viral (v-akt) oncogene homolog 1 , protein kinase B alpha , thymoma viral proto-oncogene 1 , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , CAK-beta , FADK 2 , PTK2B protein tyrosine kinase 2 beta , calcium-dependent tyrosine kinase , calcium-regulated non-receptor proline-rich tyrosine kinase , cell adhesion kinase beta , focal adhesion kinase 2 , proline-rich tyrosine kinase 2 , protein kinase B , protein-tyrosine kinase 2-beta , related adhesion focal tyrosine kinase , CADTK , CAK beta , PTK2 protein tyrosine kinase 2 beta , cellular adhesion kinase beta , protein tyrosine kinase 2 beta

GENE ID SPECIES
24185 Rattus norvegicus
11651 Mus musculus
2185 Homo sapiens
50646 Rattus norvegicus
19229 Mus musculus
486102 Canis lupus familiaris
541008 Bos taurus
421998 Gallus gallus
100157507 Sus scrofa
100342358 Oryctolagus cuniculus
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