ABCB1 Produits
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))
Catégories
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
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Catégories ABCB1 en vedette
ABCB1 Anticorps
High quality antibodies with extensive validation data.
ABCB1 Kits ELISA
Reliable ELISA kits for a wide range of species.
ABCB1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ABCB1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (7)
N° du produit
ABIN1491725
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN7265732
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, IHC (p)
Validations
- (5)
N° du produit
ABIN1491724
Quantité
100 μL
Fiche technique
Fiche technique
ABCB1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (2)
N° du produit
ABIN6965064
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965066
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965065
Quantité
96 tests
Fiche technique
Fiche technique
ABCB1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1305435
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121929
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3083531
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ABCB1
: "Microphysiological Conditions Do Not Affect MDR1-Mediated Transport of Rhodamine 123 above an Artificial Proximal Tubule." dans: Biomedicines, Vol. 11, Issue 7, (2023) (PubMed).: "Association Analysis of Single-Cell RNA Sequencing and Proteomics Reveals a Vital Role of Ca2+ Signaling in the Determination of Skeletal Muscle Development Potential." dans: Cells, Vol. 9, Issue 4, (2021) (PubMed).
: "Hypoxia-tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia." dans: ACS nano, Vol. 13, Issue 1, pp. 236-247, (2019) (PubMed).
: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." dans: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).
: "Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity." dans: The Journal of clinical investigation, Vol. 129, Issue 12, pp. 5442-5461, (2019) (PubMed).
: "MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition." dans: Gene, Vol. 652, pp. 48-58, (2018) (PubMed).
: "Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance." dans: Cell death & disease, Vol. 9, Issue 4, pp. 419, (2018) (PubMed).
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).
: "Role of P-glycoprotein inhibitors in children with drug-resistant epilepsy." dans: Acta neurologica Scandinavica, Vol. 136, Issue 6, pp. 639-644, (2018) (PubMed).
: "Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer." dans: Stem cells (Dayton, Ohio), Vol. 34, Issue 11, pp. 2613-2624, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à ABCB1
ATP binding cassette subfamily B member 1 (ABCB1), ATP binding cassette subfamily B member 1A (Abcb1a), ATP binding cassette subfamily B member 1 L homeolog (abcb1.L), ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), ATP binding cassette subfamily B member 1 (Abcb1), ABC20, Abcb1, ABCB1, CD243, CLCS, GP170, mdr, MDR1, Mdr1, Mdr1a, Mdr1b, P-GP, p-gp, PGP1, Pgy-1, PGY1, Pgy1, xemdrProtein level used designations for ABCB1
- P-glycoprotein 1
- colchicin sensitivity
- doxorubicin resistance
- multidrug resistance protein 1
- ATP-binding cassette, sub-family B (MDR/TAP), member 1
- ATP-binding cassette, subfamily B (MDR/TAP), member 1A
- multiple drug resistant 1a
- bovine P-glycoprotein
- ATP-binding cassette, subfamily B, member 1
- P-glycoprotein
- multidrug resistance p-glycoprotein
- multidrug resistance protein
- ATP-binding cassette sub-family B member 1
- P glycoprotein 1
- multidrug resistance protein 1B
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