ABCC5 Produits
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 5 (ABCC5))
Catégories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear. [provided by RefSeq, Jul 2008].
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Catégories ABCC5 en vedette
ABCC5 Anticorps
High quality antibodies with extensive validation data.
ABCC5 Kits ELISA
Reliable ELISA kits for a wide range of species.
ABCC5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
ABCC5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC
Validations
- (5)
N° du produit
ABIN302162
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (1)
- (3)
N° du produit
ABIN6266184
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7160318
Quantité
100 μg
Fiche technique
Fiche technique
ABCC5 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6964517
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6953382
Quantité
96 tests
Fiche technique
Fiche technique
ABCC5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305459
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1305461
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3137465
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits ABCC5
: "Brusatol Enhances the Chemotherapy Efficacy of Gemcitabine in Pancreatic Cancer via the Nrf2 Signalling Pathway." dans: Oxidative medicine and cellular longevity, Vol. 2018, pp. 2360427, (2018) (PubMed).: "Effects of chronic renal failure on brain drug transporters in rats." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 39-46, (2011) (PubMed).
: "Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ..." dans: The American journal of pathology, Vol. 166, Issue 1, pp. 39-48, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à ABCC5
ATP binding cassette subfamily C member 5 (ABCC5), ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (Abcc5), ATP binding cassette subfamily C member 5 (Abcc5), ATP binding cassette subfamily C member 5 L homeolog (abcc5.L), 2900011L11Rik, ABC33, abc33, abcc5, Abcc5a, Abcc5b, AI132311, EST277145, MOAT-C, moat-c, MOATC, moatc, MRP5, Mrp5, mrp5, pABC11, pabc11, SMRP, smrpProtein level used designations for ABCC5
- ATP-binding cassette sub-family C member 5
- canalicular multispecific organic anion transporter C
- multi-specific organic anion transporter C
- multidrug resistance-associated protein 5
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5b
- ATP-binding cassette, sub-family C, member 5
- MOAT-C
- SMRP
- ATP-binding cassette sub-family C (CFTR/MRP) member 5a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 5
- ATP binding cassette subfamily C member 5 L homeolog
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