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ABCB1 Protéines

(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1))

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].

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ABCB1 Protein (AA 1-1280) (His tag)

custom-made ABCB1 Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant ABCB1 Protein, UniprotID P08183

3 images

N° du produit ABIN7554517

Détails

ABCB1 Protein (AA 620-709) (GST tag)

ABCB1 Origine: Humain Hôte: Wheat germ Recombinant ELISA, WB, AP, AA

Image no. 1 for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 620-709) protein (GST tag) (ABIN1305435)

1 image

1 reference

N° du produit ABIN1305435

Détails

ABCB1 Protein (AA 491-694) (His-IF2DI Tag)

ABCB1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. ELISA, WB

Western Blotting (WB) image for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) (AA 491-694) protein (His-IF2DI Tag) (ABIN7121929)

1 image

N° du produit ABIN7121929

Détails

ABCB1 Protein (AA 392-628) (His tag)

ABCB1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

N° du produit ABIN7505266

Détails

ABCB1 Protein (GST tag)

ABCB1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant ELISA, WB, SDS

N° du produit ABIN7575669

Détails

ABCB1 Protein (His tag)

ABCB1 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % Inactive

N° du produit ABIN7668202

Détails

ABCB1 Protein (AA 1-1280) (Strep Tag)

custom-made ABCB1 Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). ELISA, WB, SDS

N° du produit ABIN3112158