Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) Kits ELISA

CYP2B6, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions CYP2B6 Anticorps (91) et CYP2B6 Protéines (4) et beaucoup plus de produits pour cette protéine.

list all ELISA KIts Gène GeneID UniProt
CYP2B6 1555 P20813
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Top CYP2B6 Kits ELISA sur

Showing 5 out of 11 products:

Catalogue No. Reactivité Sensibilité Gamme Images Quantité Livraison Prix Détails
Humain 9.75 pg/mL 39-2500 pg/mL Typical standard curve 96 Tests 15 to 18 Days
Souris 0.118 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
Souris < 0.118 ng/mL 0.312 ng/mL - 20 ng/mL   96 Tests 11 to 18 Days
Humain < 0.33 ng/mL 0.781 ng/mL - 50 ng/mL   96 Tests 11 to 18 Days
  96 Tests 2 to 3 Days

CYP2B6 Kits ELISA mieux référencés

  1. Mouse (Murine) CYP2B6 Kit ELISA pour Sandwich ELISA - ABIN426458 : Cao, Hua, Wang, Chen: Exposure of pregnant mice to triclosan impairs placental development and nutrient transport. dans Scientific reports 2017 (PubMed)

Plus Kits ELISA pour CYP2B6 partenaires d'interaction

Human Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6) interaction partners

  1. CYP2B6 metabolizer strata do not have a statistically significant association with either depression or 6-month viral suppression. In analyses restricted to participants without pre-ART depression, poorer CYP2B6 metabolism is associated with increased odds of depression. Efavirenz-metabolizing allele patterns are strongly associated with risk of incident depression in Ugandan persons living with HIV.

  2. CONCLUSIONS: This study demonstrated that BMI influences propofol pharmacokinetics after its administration as a single intravenous injection, while UGT1A9 and CYP2B6 SNPs, other clinical factors, and hemodynamic variables do not.

  3. Study concludes that CYP2B6 metabolizes nicotine stereoselectively and common CYP2B6 variants differ in nicotine metabolism activity but did not find evidence of CYP2B6 activity in human brain.

  4. No significant association was detected between CYP2B6 516G>T polymorphism and susceptibility to ARV-associated hepatotoxicity.

  5. Case Reports: CYP2B6-deficient alleles may be responsible for an increased conversion of ifosfamide into neurotoxic metabolites, leading to encephalopathy.

  6. The concentration-time curve (AUC(0(R)96)), maximum plasma concentration (Cmax), and terminal half-life (t1/2) values of Bupropion in CYP2B6*1/*4 were lower than those of CYP2B6*1/*1. The hydroxybupropion (HBUP) Cmax values in CYP2B6*4/*6 and CYP2B6*1/*4 increased by 1.12-fold and 1.97-fold, whereas the HBUP Cmax value in CYP2B6*1/*6 decreased to a value 1.64-fold lower than that in CYP2B6*1/*1

  7. CYP2B6-efavirenz analog complex provides a useful platform to investigate computationally as well as biophysically the effect of genetic polymorphisms on binding of the widely studied efavirenz.

  8. results indicate that the amino acid substitutions in the CYP2B6 variants suppressed the metabolic activation of CPS. CYP2B6 variants have altered capacity to bioactivate CPF and may affect individual susceptibility of CPF

  9. The findings of this study indicate that CYP2B6 contribute to the metabolism of MDMA to MDA in humans

  10. The first data of several CYP2B6 polymorphisms in Roma population.

  11. With consensus recommendations on downregulation, CYP2C induction, and CYP2B6 positive control.

  12. Genotyping of CYP2B6 may therefore be of value when assessing dose requirements in methadone maintenance treatment.

  13. Genomic variation in CYP2B6 may explain, at least in part, severity of Neonatal Abstinence Syndrome

  14. CYP2B6 haplotype predicts efavirenz plasma concentration in black South African HIV-1-Infected children.

  15. This is the first study that investigated the impact of the 516 G>T polymorphism of the CYP2B6 gene among HIV-positive individuals from southern Brazil. Its clinical significance indicates the need for prospective studies in this population.

  16. G(516)T CYP2B6 polymorphisms was associated with Bronchopulmonary Dysplasia susceptibility in Preterm Neonates.

  17. The deficient CYP2B6 516 T allele is associated with higher efavirenz plasma drug levels and more frequent central nervous system-related symptoms.

  18. Males with the CYP2B6 *6/*6 genotype may be less susceptible to the development of anti-tuberculosis drug-induced hepatotoxicity.

  19. CYP2B6 interindividual variability was not significantly associated with genetic variation in CYP2B6, nor was it associated with differences in gender or ethnicity, suggesting that factors other than these are largely responsible for the wide range of variability in CYP2B6 expression and activity observed among a large group of individuals/samples.

  20. Established the regression models for CYP3A4 and CYP2B6 inductions in human hepatocytes using azole compounds.

CYP2B6 profil antigène

Antigen Summary

This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Gene names and symbols associated with CYP2B6

  • cytochrome P450 family 2 subfamily B member 6 (CYP2B6) anticorps
  • cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6) anticorps
  • cytochrome P450 family 2 subfamily B member 6 L homeolog (cyp2b6.L) anticorps
  • cytochrome P450 2B11 (CYP2B6) anticorps
  • cytochrome P450 subfamily 2B (CYP2B6) anticorps
  • cytochrome P450 2B11-like (LOC100068603) anticorps
  • CPB6 anticorps
  • CYP2B anticorps
  • CYP2B6 anticorps
  • CYP2B7 anticorps
  • CYP2B7P anticorps
  • CYP2B11 anticorps
  • CYP2B30 anticorps
  • CYPIIB6 anticorps
  • CYPIIB11 anticorps
  • EFVM anticorps
  • IIB1 anticorps
  • P450 anticorps

Protein level used designations for CYP2B6

1,4-cineole 2-exo-monooxygenase , cytochrome P450 2B6 , cytochrome P450 IIB1 , cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6 , cytochrome P450 CYP2B30 , cytochrome P450, family 2, subfamily B, polypeptide 6 , cytochrome P450 PBD-2 , cytochrome P450, family 2, subfamily B, polypeptide 11 , cytochrome P450 subfamily 2B , Cytochrome P450 2B6 , LOW QUALITY PROTEIN: cytochrome P450 2B11-like , cytochrome P450 2B11-like

1555 Homo sapiens
678687 Macaca mulatta
494798 Xenopus laevis
474177 Canis lupus familiaris
504769 Bos taurus
100068603 Equus caballus
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