CYP2B6 Produits
(Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))
Catégories
This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described\; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008].
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Catégories CYP2B6 en vedette
CYP2B6 Anticorps
High quality antibodies with extensive validation data.
CYP2B6 Kits ELISA
Reliable ELISA kits for a wide range of species.
CYP2B6 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CYP2B6 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (5)
N° du produit
ABIN1679474
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (2)
- (3)
N° du produit
ABIN655056
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (3)
N° du produit
ABIN7258000
Quantité
200 μL
Fiche technique
Fiche technique
CYP2B6 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6955243
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966236
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955242
Quantité
96 tests
Fiche technique
Fiche technique
CYP2B6 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350963
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3078137
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7407754
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CYP2B6
: "Xenobiotic Nuclear Receptor Signaling Determines Molecular Pathogenesis of Progressive Familial Intrahepatic Cholestasis." dans: Endocrinology, Vol. 159, Issue 6, pp. 2435-2446, (2019) (PubMed).: "Exposure of pregnant mice to triclosan impairs placental development and nutrient transport." dans: Scientific reports, Vol. 7, pp. 44803, (2017) (PubMed).
: "Characterization of feline cytochrome P450 2B6." dans: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 47, Issue 2, pp. 93-102, (2017) (PubMed).
: "Selective induction of hepatic cytochrome P450 2B activity by leelamine in vivo, as a potent novel inducer." dans: Archives of pharmacal research, Vol. 38, Issue 5, pp. 725-33, (2015) (PubMed).
: "Hepatic expression of detoxification enzymes is decreased in human obstructive cholestasis due to gallstone biliary obstruction." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0120055, (2015) (PubMed).
: "Combination therapy of cyclophosphamide and Rhizoma Paridis Saponins on anti-hepatocarcinoma mice and effects on cytochrome p450 enzyme expression." dans: Steroids, Vol. 80, pp. 1-6, (2014) (PubMed).
: "The role of cytochromes p450 and aldo-keto reductases in prognosis of breast carcinoma patients." dans: Medicine, Vol. 93, Issue 28, pp. e255, (2014) (PubMed).
: "Self-limited versus delayed resolution of acute inflammation: temporal regulation of pro-resolving mediators and microRNA." dans: Scientific reports, Vol. 2, pp. 639, (2012) (PubMed).
: "Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo." dans: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 1, pp. 54-63, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à CYP2B6
cytochrome P450 family 2 subfamily B member 6 (CYP2B6), cytochrome P450 family 4 subfamily F member 3 (CYP4F3), cytochrome P450, family 2, subfamily B, polypeptide 6 (CYP2B6), cytochrome P450 family 2 subfamily B member 6 L homeolog (cyp2b6.L), cytochrome P450 2B11 (CYP2B6), cytochrome P450, family 21, subfamily a, polypeptide 1 (Cyp21a1), cytochrome P450 subfamily 2B (CYP2B6), cytochrome P450 2B11-like (LOC100068603), 21-OH, 21OH, 21OHA, 21OHB, CPB6, CPF3, CYP2B, CYP2B6, CYP2B7, CYP2B7P, CYP2B11, CYP2B30, CYP4F, Cyp21, Cyp21-ps1, Cyp21a2-ps, Cyp21a2ps, Cyp21B, CYP21OH-A, CYPIIB6, CYPIIB11, EFVM, IIB1, LTB4H, Oh21-1, Oh21-2, P450Protein level used designations for CYP2B6
- 1,4-cineole 2-exo-monooxygenase
- cytochrome P450 2B6
- cytochrome P450 IIB1
- cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
- CYPIVF3
- cytochrome P-450
- cytochrome P450 4F3
- cytochrome P450, subfamily IVF, polypeptide 3 (leukotriene B4 omega hydroxylase)
- cytochrome P450-LTB-omega
- leukotriene B4 omega hydroxylase
- leukotriene-B(4) 20-monooxygenase 2
- leukotriene-B(4) omega-hydroxylase 2
- leukotriene-B4 20-monooxygenase
- cytochrome P450 CYP2B30
- cytochrome P450, family 2, subfamily B, polypeptide 6
- cytochrome P450 PBD-2
- cytochrome P450, family 2, subfamily B, polypeptide 11
- 21-OHase
- 21-hydroxylase
- cytochrome P-450c21
- cytochrome P450 21
- cytochrome P450 XXI
- cytochrome P450 hydroxylase A
- cytochrome P450, 21, pseudogene
- cytochrome P450, 21, steroid 21 hydroxylase
- cytochrome P450, family 21, subfamily a, polypeptide 2, pseudogene
- cytochrome P450-C21
- steroid 21 hydroxylase
- steroid 21-hydroxylase
- cytochrome P450 subfamily 2B
- Cytochrome P450 2B6
- LOW QUALITY PROTEIN: cytochrome P450 2B11-like
- cytochrome P450 2B11-like
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