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CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. De plus, nous expédions CYP2C19 Anticorps (38) et CYP2C19 Protéines (3) et beaucoup plus de produits pour cette protéine.
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CYP2C19 polymorphisms significantly impacted systemic exposure and metabolism pathways of BMS-823778 in humans.
Human but not rat liver proteins immunoblotting allowed us to characterize the novel LM antibodies and to identify CYP (Montrer PPIG Kits ELISA)-2C19 as human antigen
The frequency of primary outcome was significantly higher in patients carrying CYP2C19*2 AG/AA genotype receiving PPIs compared with the same genotype in those not receiving PPIs. The PPIs used in patients carrying CYP2C19*2 AG/AA was independently associated with the primary outcome after adjusting for other risk factors.
PPI therapy in children with *17 alleles may be better optimized with CYP2C19 genotype-guided dosing prior to pH probe testing.
The findings of this study indicate that CYP2C19 contribute to the metabolism of MDMA to MDA in humans
Patients with CYP2C19*2 were at increased risk and CYP2C19*2, CYP3A5 (Montrer CYP3A5 Kits ELISA)*3 and GSTP1 (Montrer GSTP1 Kits ELISA) have synergistic influence on CYC (Montrer CYCS Kits ELISA) failure.
Consensus has yet to be reached on which CYP2D6 (Montrer CYP2D6 Kits ELISA) and CYP2C19 star alleles to include on pharmacogenetic testing panels and pharmacogenetic results reporting could be considerably improved
The impact of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple eradication therapy in Slavic patients appears significant.
A total of 42.0% carried >/=1 CYP2C19*2 allele.
Implementing a CYP2C19 genotype-guided approach to antiplatelet therapy.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.
cytochrome P450 2C
, (R)-limonene 6-monooxygenase
, (S)-limonene 6-monooxygenase
, (S)-limonene 7-monooxygenase
, S-mephenytoin 4-hydroxylase
, cytochrome P-450 II C
, cytochrome P450 2C19
, cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19
, cytochrome P450-11A
, cytochrome P450-254C
, flavoprotein-linked monooxygenase
, mephenytoin 4'-hydroxylase
, mephenytoin 4-hydroxylase
, microsomal monooxygenase
, xenobiotic monooxygenase